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GenomicsExpression data from SUN2 downstream
Expression data from SUN2 downstream
PRJNA631900 | ENA
TranscriptomicsExpression data from SUN2 downstream
SAD1/UNC84 domain protein-2(SUN2) is a member of the inner nuclear membrane LINC (linker of nucleoskeleton and cytoskeleton) complex, which maintains nuclear structure by connecting the nuclear lamina to the cytoskeleton. SUN2 is located at the inner nuclear membrane, where it extends into the perin...
ORGANISM(S): Homo sapiens 
2023-05-15 | GSE150356 | GEO
GenomicsGenome-wide CRISPR-Cas9 screen (TKOv3) data on SUN2 degradation
Genome-wide CRISPR-Cas9 screen (TKOv3) data on SUN2 degradation
PRJEB54102 | ENA
ProteomicsPrimary human MSCs treated with two different RNAi against SUN2
Cells resident in tissues must be resilient to the physical demands of their surroundings. Our current understanding of cellular mechano-signalling is largely based on static systems, but these models do not reproduce the dynamic nature of living tissue. Here, we examined the time-resolved response ...
ORGANISM(S): Homo sapiens (Human) 
2019-04-24 | PXD012948 | Pride
Sun2 Msc Rnai 
ProteomicsDoxycycline-induced SUN2 overexpression in Y-201 MSC cell line
Cells resident in tissues must be resilient to the physical demands of their surroundings. Our current understanding of cellular mechano-signalling is largely based on static systems, but these models do not reproduce the dynamic nature of living tissue. Here, we examined the time-resolved response ...
ORGANISM(S): Homo sapiens (Human) 
2019-04-24 | PXD012863 | Pride
Sun2 Msc Overexpression 
GenomicsPerinuclear force regulates SUN2 dynamics and distribution on the nuclear envelope for proper nuclear mechanotransduction
Perinuclear force regulates SUN2 dynamics and distribution on the nuclear envelope for proper nuclear mechanotransduction
PRJNA887402 | ENA
TranscriptomicsPerinuclear force regulates SUN2 dynamics and distribution on the nuclear envelope for proper nuclear mechanotransduction
The trans-luminal LINC (Linker of Nucleoskeleton and Cytoskeleton) complex plays a central role in nuclear mechanotransduction by coupling the nucleus with cytoskeleton. High spatial density and active dynamics of LINC complex have hindered its precise characterization for the understanding of under...
ORGANISM(S): Homo sapiens 
2022-10-12 | GSE214854 | GEO
UnknownSUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.
Not available
S-EPMC4810566 | biostudies-literature
UnknownSubcellular localization of SUN2 is regulated by lamin A and Rab5.
Not available
S-EPMC3105078 | biostudies-literature
UnknownSUN2 exerts tumor suppressor functions by suppressing the Warburg effect in lung cancer.
Not available
S-EPMC4674702 | biostudies-literature
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