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TranscriptomicsThe dsRBP and inactive editor, ADR-1, utilizes dsRNA binding to regulate A-to-I RNA editing across the C. elegans transcriptome
Purpose: The purpose of this experiment is to expand the repertoire of C. elegans edited transcripts and identify the roles of ADR-1 as indirect regulator of editing and ADR-2 as the only active deaminase in vivo. Methods: Strand-specific RNA sequencing of wild-type and adr mutant worms, followed by...
ORGANISM(S): Caenorhabditis elegans 
2014-01-20 | E-GEOD-51556 | biostudies-arrayexpress
TranscriptomicsDistinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_mouse]
TDP-43, FUS, and TAF15 are implicated in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. We integrate CLIP-seq and RNA Bind-N-Seq technologies to discover that TAF15 binds to ~4,900 RNAs enriched for GGUA motifs. In the mouse brain, TAF15 and FUS, but not TDP-43, exhibit strikingly ...
ORGANISM(S): Mus musculus 
2016-07-05 | E-GEOD-77703 | biostudies-arrayexpress
Unknown(E)-4-[(4-Methoxy-phen-yl)imino-meth-yl]-N,N-dimethyl-aniline.
Not available
S-EPMC2968506 | biostudies-literature
UnknownA method to generate capture baits for targeted sequencing.
Not available
S-EPMC10359599 | biostudies-literature
UnknownThe dsRBP and inactive editor ADR-1 utilizes dsRNA binding to regulate A-to-I RNA editing across the C. elegans transcriptome.
Not available
S-EPMC3959997 | biostudies-literature
UnknownAsymmetric chromatid segregation in cardiac progenitor cells is enhanced by Pim-1 kinase.
Not available
S-EPMC3357328 | biostudies-literature
TranscriptomicsDistinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human]
TDP-43, FUS, and TAF15 are implicated in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. We integrate CLIP-seq and RNA Bind-N-Seq technologies to discover that TAF15 binds to ~4,900 RNAs enriched for GGUA motifs. In the mouse brain, TAF15 and FUS, but not TDP-43, exhibit strikingly ...
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-77702 | biostudies-arrayexpress
TranscriptomicsDistinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability]
TDP-43, FUS, and TAF15 are implicated in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. We integrate CLIP-seq and RNA Bind-N-Seq technologies to discover that TAF15 binds to ~4,900 RNAs enriched for GGUA motifs. In the mouse brain, TAF15 and FUS, but not TDP-43, exhibit strikingly ...
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-77704 | biostudies-arrayexpress
UnknownA hybridization target enrichment approach for pathogen genomics.
Not available
S-EPMC10653935 | biostudies-literature
UnknownIncreased mitotic rate coincident with transient telomere lengthening resulting from pim-1 overexpression in cardiac progenitor cells.
Not available
S-EPMC3479348 | biostudies-literature
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