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ProteomicsIdentifying secondary processes implicated in nemaline myopathy pathophysiology
Nemaline myopathy (NM) is a genetically and clinically heterogeneous disease that is diagnosed based on the presence of nemaline rods on skeletal muscle biopsy. While NM has typically been classified by causative genes, disease severity or prognosis cannot be predicted well. The common pathological ...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD042201 | Pride
Nemaline myopathy Neb cko Acta1 
TranscriptomicsTranscriptional reprogramming of tumor-associated endothelial cells by disruption of TNF-M-NM-1 signaling
Endothelial inflammation contributes to the pathogenesis of numerous human diseases; however, the role of tumor endothelial inflammation in the growth of experimental tumors and its influence on the prognosis of human cancers is less understood. TNF-M-NM-1, an important mediator of tumor stromal inf...
ORGANISM(S): Mus musculus 
2012-10-20 | E-GEOD-33253 | biostudies-arrayexpress
TranscriptomicsTranscriptional and Phenotypic Reprogramming of Tumors by Host Stroma Deficient in TNFα Signaling
Background: We previously demonstrated that B16F1 melanoma tumors growing in syngeneic germline-deleted TNFR1,2 -/- mice were more sensitive to ionizing radiation (IR) compared to tumors growing in C57BL/6 wild-type mice; however, the mechanisms linked to this difference in radiosensitivity are not ...
ORGANISM(S): Mus musculus 
2010-07-20 | E-GEOD-23002 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse quantitative trait loci (QTLs) in uantitative trait loci (QTLs) and brain to identify genes and loci that control hematopoietic stem cell (HSC) functioning
We have combined large-scale mRNA expression and gene mapping methods to identify genes and loci that control hematopoietic stem cell (HSC) functioning. mRNA expression levels were measured in purified HSC isolated from a panel of densely genotyped recombinant inbred mouse strains. Quantitative trai...
ORGANISM(S): Mus musculus 
2007-11-16 | E-GEOD-2031 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of purified populations of normal human breast luminal and myoepithelial cells
Purified populations of normal human breast luminal and myoepithelial cells were compared with cDNA microarray analysis.
ORGANISM(S): Homo sapiens 
2004-05-04 | E-MEXP-36 | biostudies-arrayexpress
UnknownBaseline Features and Reasons for Nonparticipation in the Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM) Study, a Colorectal Cancer Screening Trial.
Not available
S-EPMC10336619 | biostudies-literature
UnknownThe Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19.
Not available
S-EPMC9447373 | biostudies-literature
UnknownPolygenic risk score for type 2 diabetes shows context-dependent effects across populations.
Not available
S-EPMC12488948 | biostudies-literature
UnknownGenome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.
Not available
S-EPMC4063682 | biostudies-literature
UnknownMetformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol.
Not available
S-EPMC12303861 | biostudies-literature
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