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TranscriptomicsMapping the Genetic Architecture of Gene Expression in Human Liver
To uncover the genetic determinants affecting expression in a metabolically active tissue relevant to the study of obesity, diabetes, atherosclerosis, and other common human diseases, we profiled 427 human liver samples on a comprehensive gene expression microarray targeting greater than 40,000 tran...
ORGANISM(S): Homo sapiens 
2008-05-07 | E-GEOD-9588 | biostudies-arrayexpress
TranscriptomicsExpression profile of liver samples from subjects at the time of Roux en Y gastric bypass surgery.
To map the genetics of gene expression in metabolically relevant tissues and investigate the diversity of expression SNPs (eSNPs) in multiple tissues from the same individual, we collected four tissues from approximately 1,000 patients undergoing Roux-en-y gastric bypass and clinical traits associat...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-24293 | biostudies-arrayexpress
TranscriptomicsExpression profile of omental adipose samples from subjects at the time of Roux en Y gastric bypass surgery.
To map the genetics of gene expression in metabolically relevant tissues and investigate the diversity of expression SNPs (eSNPs) in multiple tissues from the same individual, we collected four tissues from approximately 1,000 patients undergoing Roux-en-y gastric bypass and clinical traits associat...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-24294 | biostudies-arrayexpress
TranscriptomicsExpression profile of subcutaneous adipose samples from subjects at the time of Roux en Y gastric bypass surgery.
To map the genetics of gene expression in metabolically relevant tissues and investigate the diversity of expression SNPs (eSNPs) in multiple tissues from the same individual, we collected four tissues from approximately 1,000 patients undergoing Roux-en-y gastric bypass and clinical traits associat...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-24297 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of human prefrontal cortex brain tissues
Dissecting the shared etiology of different diseases could benefit from a systematic search for associated molecules and their interactions. We investigated genome-wide disruptions in the co-regulation of genes in two neurodegenerative diseases, Alzheimer's or Huntington's disease (AD or HD), using ...
ORGANISM(S): Homo sapiens 
2014-07-31 | E-GEOD-33000 | biostudies-arrayexpress
TranscriptomicsMulti-tissue gene expression profiles of human brain (CR)
The genetics of complex disease produce alterations in molecular interactions of cellular pathways which collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer´s disease (LOAD), we constructed g...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-44768 | biostudies-arrayexpress
TranscriptomicsMulti-tissue gene expression profiles of human brain (PFC)
The genetics of complex disease produce alterations in molecular interactions of cellular pathways which collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer´s disease (LOAD), we constructed g...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-44770 | biostudies-arrayexpress
TranscriptomicsMulti-tissue gene expression profiles of human brain (VC)
The genetics of complex disease produce alterations in molecular interactions of cellular pathways which collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer´s disease (LOAD), we constructed g...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-44771 | biostudies-arrayexpress
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