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TranscriptomicsMepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease
For the clinical treatment of chronic obstructive pulmonary disease (COPD), it is important not only to improve the airflow limitation by bronchodilation but also to suppress emphysema by controlling inflammation. In this study, we have screened for compounds that prevent elastase-induced airspace ...
ORGANISM(S): Mus musculus 
2013-11-13 | E-GEOD-50836 | biostudies-arrayexpress
TranscriptomicsDevelopment and Preclinical Efficacy of Novel Transforming Growth Factor-β1 (TGFβ1) siRNAs for Pulmonary Fibrosis
Idiopathic pulmonary fibrosis is a chronic devastating disease of unknown etiology. No therapy is currently available. A growing body of evidence supports the role of TGFβ1 as the major player in the pathogenesis of the disease. This study designed novel human- and mouse-specific siRNAs and siRNA/DN...
ORGANISM(S): Mus musculus 
2011-11-22 | E-GEOD-28122 | biostudies-arrayexpress
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