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ProteomicsMouse osteoclast-small extracellular vesicles LC-MSMS
Small extracellular vesicles secreted from maturing osteoclasts were collected and analyzed for identifying their protein components
ORGANISM(S): Mus musculus (Mouse) 
2018-09-06 | PXD010500 | Pride
Lc-msms Mouse Osteoclast Small extracellular vesicles 
UnknownCytosolic N-GlcNAc proteins are formed by the action of endo-β-N-acetylglucosaminidase.
Not available
S-EPMC7508226 | biostudies-literature
TranscriptomicsExpression data of the human hepatoblastoma cell line HepG2 treated with TGF-beta
Smad2/3 are transcription factors that engage in TGF-beta-induced transcription. We determined and analyzed HepG2 and Hep3B-specific Smad2/3 binding sites by ChIP-chip. We used expression microarrays to compare the Smad2/3 and HNF4alpha binding sites identified by ChIP-chip or ChIP-seq, respectively...
ORGANISM(S): Homo sapiens 
2011-06-08 | E-GEOD-28590 | biostudies-arrayexpress
UnknownN-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1.
Not available
S-EPMC6170171 | biostudies-literature
TranscriptomicsSmall-RNA asymmetry is directly driven by mammalian Argonautes
Asymmetric selection of single-stranded guide RNAs from double-stranded RNA (dsRNA) precursors is crucial for RNA silencing-mediated gene regulation. However, the precise mechanisms for small RNA asymmetry remain unclear, especially since asymmetric selection can still occur under depletion of putat...
ORGANISM(S): Mus musculus 
2015-06-15 | E-GEOD-66022 | biostudies-arrayexpress
TranscriptomicsHistone H3K36 trimethylation is essential for multiple silencing mechanisms in fission yeast.
In budding yeast, Set2 catalyzes di- and trimethylation of H3K36 (H3K36me2 and H3K36me3) via an interaction between its SRI domain and C-terminal repeats of RNA polymerase II (Pol2) phosphorylated at Ser2 and Ser5 (CTD-S2,5-P). H3K36me2 recruits the Rpd3S histone deacetylase complex to repress crypt...
ORGANISM(S): Schizosaccharomyces pombe 
2016-02-04 | E-GEOD-66821 | biostudies-arrayexpress
UnknownCryo-electron micrographs of hAQP2 in DDM
Not available
EMPIAR-11592 | biostudies-other
TranscriptomicsTranscriptome in alveolar epithelial type II-like cells differentiated from human lung progenitor cells
Resident stem/progenitor cells in lungs are important for tissue homeostasis and repair. We isolated human lung progenitor cells and named alveolar epithelial progenitor cells (AEPCs)(Fujino N, et al. 2011. Lab Invest. 91:363). AEPCs have phenotypes of both alveolar epithelial type II (ATII) cells a...
ORGANISM(S): Homo sapiens 
2012-10-11 | E-GEOD-33825 | biostudies-arrayexpress
TranscriptomicsExpression data from murine follicular dendritic cells
Germinal centers (GCs) are clusters of activated B cells built on stromal cells known as follicular dendritic cells (FDCs). In the Peyer’s patches (PPs), GCs are chronically induced by bacteria and are the major sites for generation of gut IgA immune responses. Whether FDCs directly contribute to ...
ORGANISM(S): Mus musculus 
2010-07-30 | E-GEOD-19401 | biostudies-arrayexpress
MetabolomicsSeed Metabolome Analysis of a Transgenic Rice Line Expressing Cholera Toxin B-subunit
Rice (Oryza sativa L.) is a candidate crop for production of plant-based vaccines by genetic engineering technologies. MucoRice-CTB has been developed as a rice-seed-based vaccine against cholera by transgenic expression of modified cholera toxin B-subunit (CTB) under the RNA interference (RNAi)-med...
2017-08-30 | MTBLS437 | MetaboLights
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