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TranscriptomicsOverexpression of NtmybA2 in tobacco BY-2 cells
Promoters of many G2/M phase-specific genes in plants contain mitosis-specific activator (MSA) elements, which act as G2/M phase-specific enhancers and bind with R1R2R3-Myb transcription factors. A least three R1R2R3-Myb proteins are expressed in tobacco (Nicotiana tabacum). To examine the genome-wi...
ORGANISM(S): Nicotiana tabacum 
2010-05-22 | E-GEOD-14251 | biostudies-arrayexpress
TranscriptomicsExpression data from Arabidopsis myb3r mutants
Temporal and spatial regulation of cell division is central for generating multicellular organs with predictable sizes and shapes. However, it remains largely unclear how genes with mitotic functions are transcriptionally regulated during organogenesis in plants. Here, we showed that a group of R1R2...
ORGANISM(S): Arabidopsis thaliana 
2015-03-31 | E-GEOD-52298 | biostudies-arrayexpress
TranscriptomicsStudy of microRNA associated with metforminM-bM-^@M-^Ys anti-tumor effect
The miRNAs expression was markedly altered with the treatment of metformin in vitro and in vivo and various miRNAs induced by metformin also may contribute to tumor growth in vitro and in vivo. Using a custom microarray platform, we analyzed the expression levels of 985 human miRNA probes in the cel...
ORGANISM(S): Homo sapiens 
2012-04-04 | E-GEOD-30289 | biostudies-arrayexpress
ProteomicsEpigenetic mechanisms to propagate histone acetylation by p300/CBP
Histone acetylation is important for the activation of gene transcription but little is known about its direct ‘read/write’ mechanisms. Here, we report cryo-electron microscopy structures in which a p300/CBP multidomain monomer recognizes histone H4 N-terminal tail (NT) acetylation (ac) in a nucleos...
ORGANISM(S): Homo sapiens (Human) 
2023-05-08 | PXD040835 | Pride
P300/cbp Histone Acetylation 
TranscriptomicsCell cycle-regulated gene expression in tobacco cells
Tobacco BY-2 cells can be highly synchronized by treatment with an inhibitor of DNA synthesis, aphidicolin. For comprehensive understanding of cell cycle-regulated gene expression in tobacco, microarray analysis was conducted in synchronized cultures of BY-2 cells. Cells were treated with aphidicoli...
ORGANISM(S): Nicotiana tabacum 
2010-05-22 | E-GEOD-14250 | biostudies-arrayexpress
ProteomicsOvercoming off-targets: Assessing western blot signals for Bcnt/Cfdp1, a tentative component of the chromatin remodeling complex
The mammalian Bucentaur/Craniofacial developmental protein 1 (Bcnt/Cfdp1) is a tentative component of the Srcap (SNF2-Related CBP Activator Protein) chromatin remodeling complex, but little is known about its properties, partly because few antibodies are available to detect the endogenous protein.　W...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-03 | PXD019016 | Pride
Bcnt 
TranscriptomicsEffect of low-Tw treatment before panicle initiation on the chilling response of spikelets at the booting stage in rice.
In rice (Oryza sativa L.), chilling-induced male sterility increased when plants experienced low water temperature (Tw, 18 M-BM-0C for 14 days) before panicle initiation. The number of mature pollen grains after chilling at the booting stage (12 M-BM-0C for 5 days) was only approximately 45% of tota...
ORGANISM(S): Oryza sativa 
2014-12-22 | E-GEOD-59221 | biostudies-arrayexpress
UnknownA hydrogen peroxide-forming NADH oxidase that functions as an alkyl hydroperoxide reductase in Amphibacillus xylanus.
Not available
S-EPMC94650 | biostudies-literature
ProteomicsThe methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
Post-translational methylation plays a crucial role in regulating and optimizing protein function. Protein histidine methylation, occurring as the two isomers 1- and 3- methylhistidine (1MH and 3MH), was first reported five decades ago, but remains largely unexplored. Here we report that METTL9 is a...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-11-23 | PXD022067 | Pride
Metylation histidine mettl9 
TranscriptomicsTranscriptomic analysis of the myb3r1 myb3r4 double mutant in Arabidopsis thaliana
R1R2R3-Myb proteins represent an evolutionarily conserved class of Myb family proteins important for cell cycle regulation and differentiation in eukaryotic cells. In plants, this class of Myb proteins are believed to play important roles in cell cycle regulation through transcriptional regulation o...
ORGANISM(S): Arabidopsis thaliana 
2011-09-06 | E-GEOD-29433 | biostudies-arrayexpress
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