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BACKGROUND: While many authorities theorize that cancer vaccines are too weak to be widely effective, there are quite a few reports with clearly demonstrated, significant clinical benefit in some patients. The literature of cellular cancer immunotherapies shows that 53% (78/147) of phase II st...
ORGANISM(S): Homo sapiens (Human) 
2022-06-23 | PXD020304 | Pride
Molecular profiling of SV-BR-1-GM, a clinically effective GM-CSF-secreting human breast cancer cell line
The SV-BR-1 cell line was derived from a chest wall lesion of a breast cancer patient. SV-BR-1 cells were stably transfected with CSF2 (encoding GM-CSF), resulting in the SV-BR-1-GM cell line. Following irradiation to prevent cell replication, both SV-BR-1 (Wiseman and Kharazi, The Open Breast Cance...
ORGANISM(S): Homo sapiens 
2018-03-23 | GSE112239 | GEO
Genomics
SV-BR-1-GM, a GM-CSF overexpressing breast cancer cell line
NADPH dependent phagocytic oxidase, by producing hydroxyradicals such as hydrogen peroxide, is essential for host defense against Salmonella infection. We used gene array analysis to identify Salmonella enterica serovar Typhimurium genes regulated by NADPH dependent phagocytic oxidase intracellularl...
ORGANISM(S): Salmonella typhimurium 
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