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TranscriptomicsDifferential gene expression in stellate sympathetic ganglia after cardiac pressure overload
Transcriptom analysis of stellate sympathetic ganglia after 8 weeks of cardiac pressure overload caused by transverse aortic constriction. Comparative transcriptome analysis was determined using the GeneChip Mouse Genome 430 2.0 Array (Affymetrix, Santa Clara, CA, USA). Six microarrays from stellat...
ORGANISM(S): Mus musculus 
2010-02-25 | E-GEOD-18004 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of gene expression in NGF-deprived sympathetic neurons identifies molecular pathways associated with cell death
Developing sympathetic neurons depend on nerve growth factor (NGF) for survival and die by apoptosis after NGF withdrawal. This process requires de novo gene expression but only a small number of genes induced by NGF deprivation have been identified so far. We have used Affymetrix Exon arrays to stu...
ORGANISM(S): Rattus norvegicus 
2013-01-17 | E-MTAB-696 | biostudies-arrayexpress
TranscriptomicsFunctional Connection with Cardiac Tissues Confers Maturation Phenotypes in hPSC-Derived PHOX2B::GFP Expressing Sympathetic Neurons
Neurons derived from human pluripotent stem cells (hPSCs) are a remarkable tool for modeling human neural development and diseases. However, it remains largely unknown whether the hPSC-derived neurons can be functionally coupled with their target tissues in vitro, which is essential for understandin...
ORGANISM(S): Homo sapiens 
2016-07-01 | E-GEOD-80689 | biostudies-arrayexpress
ProteomicsRegulatory function of sympathetic innervation on the endo/lysosomal trafficking of acetylcholine receptor
Regulation of membrane receptors involves management of endocytosis. At the neuromuscular junction, the synapse between skeletal muscle and motoneuron, proper density of the major receptor, the acetylcholine receptor, is of utmost importance for sustaining life in context of mobility. Recent work ha...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-01 | PXD021601 | Pride
Acetylcholine receptor Neuromuscular junction Sympathectomy Sympathetic nervous system Skeletal muscle Endo/lysosomal trafficking 
ProteomicsProteomic characterization of media conditioned by embryonic sympathetic ganglia and dorsal root ganglia
Embryonic malignant transformation is concomitant to organogenesis, often affecting multipotent and migratory progenitors. Neuroblastoma (NB) is an emblematic example, arising from neural crest progenitors and characterized by a high heterogeneity and a widely disseminated clinical presentation. Met...
ORGANISM(S): Mus musculus (Mouse) Gallus gallus (Chicken) 
2022-05-04 | PXD027499 | Pride
Chicken Sympathetic ganglia Conditioned medium Dorsal root ganglia Mouse Nanolc-ms/ms 
TranscriptomicsscRNA-seq of mouse sympathetic ganglia cells under control, cold-exposure, and microbiota-depletion conditions
We performed scRNA-seq analysis on sympathetic ganglia, including the superior cervical ganglion (SCG), stellate ganglion (SG), and coeliac–superior mesenteric ganglion (CG-SMG). Comparative analysis of the transcriptomic profiling revealed molecularly distinct cell subtypes. We then performed scRNA...
ORGANISM(S): Mus musculus 
2025-11-23 | E-MTAB-15945 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse vascular segments were isolated from 22 embryos at E13.5 to investigate the role of endothelin in SCG axon pathfinding
Sympathetic neurons of SCG (Superior Cervical Ganglia) send axonal projections either along the external carotid arteries to innervate the salivary glands, or along the internal carotid arteries to the lacrimal and pineal glands, the eye, blood vessels and skin of the head, and the mucosa of the ora...
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-10360 | biostudies-arrayexpress
TranscriptomicsSAGE libraries from cell bodies and axons of NGF-differentiated sympathetic neurons
The subcellular localization of specific mRNAs is an evolutionary conserved mechanism that underlies the establishment of cellular polarity and specialized cell functions. In neurons, mRNA trafficking and local protein translation in dendrites provides an important mechanism that mediates synaptic ...
ORGANISM(S): Rattus norvegicus 
2010-01-30 | E-GEOD-13788 | biostudies-arrayexpress
TranscriptomicsExpression data from sympathetic nervous system of KI Alk F1178L mice
Neuroblastoma is an embryonal neoplasm that remains of dramatic prognosis in its aggressive forms. Activating mutations of the ALK tyrosine kinase receptor have been identified in sporadic and familial cases of this cancer. We generated knock-in mice carrying an F1178L Alk mutation corresponding to ...
ORGANISM(S): Mus musculus 
2014-06-24 | E-GEOD-46584 | biostudies-arrayexpress
ProteomicsElectroacupuncture Activated Local Sympathetic Noradrenergic Signaling to relieve synovitis and referred pain behaviors in KOA Rats
Electroacupuncture Activated Local Sympathetic Noradrenergic Signaling to relieve synovitis and referred pain behaviors in KOA Rats
ORGANISM(S): Rattus Norvegicus 
2022-11-29 | PXD038461 |
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