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TranscriptomicsExpression data from sympathetic nervous system of KI Alk F1178L mice
Neuroblastoma is an embryonal neoplasm that remains of dramatic prognosis in its aggressive forms. Activating mutations of the ALK tyrosine kinase receptor have been identified in sporadic and familial cases of this cancer. We generated knock-in mice carrying an F1178L Alk mutation corresponding to ...
ORGANISM(S): Mus musculus 
2014-06-24 | E-GEOD-46584 | biostudies-arrayexpress
GenomicsMotor nerves direct the development of the sympathetic nervous system
Motor nerves direct the development of the sympathetic nervous system
PRJNA1088542 | ENA
TranscriptomicsExpression analysis of superior cervical ganglion from backcrossed TH-MYCN transgenic mice
Neuroblastoma susceptibility in TH-MYN mice is heavily influence by mouse strain background. We have combined linkage analysis of tumor susceptibility with expression QTL analysis of superior cervical ganglia (pure peripheral symptathetic nervous tissue) to identify genes underlying tumor formation...
ORGANISM(S): Mus musculus 
2015-01-30 | E-GEOD-59675 | biostudies-arrayexpress
TranscriptomicsMotor nerves direct the development of the sympathetic nervous system
The sympathetic nervous system controls a wide spectrum of bodily functions including operation of vessels, cardiac rhythm, and the “flight or fight response”. Sympathetic neurons, which are neural crest-derived, develop in coordination with presynaptic motor nerves extending from the central nervou...
ORGANISM(S): Mus musculus 
2024-07-14 | GSE261748 | GEO
UnknownThe sympathetic nervous system alterations in human hypertension.
Not available
S-EPMC4367954 | biostudies-literature
ProteomicsRegulatory function of sympathetic innervation on the endo/lysosomal trafficking of acetylcholine receptor
Regulation of membrane receptors involves management of endocytosis. At the neuromuscular junction, the synapse between skeletal muscle and motoneuron, proper density of the major receptor, the acetylcholine receptor, is of utmost importance for sustaining life in context of mobility. Recent work ha...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-01 | PXD021601 | Pride
Acetylcholine receptor Neuromuscular junction Sympathectomy Sympathetic nervous system Skeletal muscle Endo/lysosomal trafficking 
UnknownTrkB/BDNF signalling patterns the sympathetic nervous system.
Not available
S-EPMC4586040 | biostudies-literature
TranscriptomicsGene expression analysis of SCG sympathetic neurons with loss of Egr3
The transcription factor Egr3 has been shown to have a cell autonomous role in sympathetic nervous system (SNS) development. We utilized microarray analysis to identify potential downstream target genes deregulated with loss of Egr3. Both conditions were in the null Bax background to prevent apoptos...
ORGANISM(S): Mus musculus 
2013-03-22 | E-GEOD-41290 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse vascular segments were isolated from 22 embryos at E13.5 to investigate the role of endothelin in SCG axon pathfinding
Sympathetic neurons of SCG (Superior Cervical Ganglia) send axonal projections either along the external carotid arteries to innervate the salivary glands, or along the internal carotid arteries to the lacrimal and pineal glands, the eye, blood vessels and skin of the head, and the mucosa of the ora...
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-10360 | biostudies-arrayexpress
TranscriptomicsExpression data from sympathetic nervous system of KI Alk F1178L mice
Neuroblastoma is an embryonal neoplasm that remains of dramatic prognosis in its aggressive forms. Activating mutations of the ALK tyrosine kinase receptor have been identified in sporadic and familial cases of this cancer. We generated knock-in mice carrying an F1178L Alk mutation corresponding to ...
ORGANISM(S): Mus musculus 
2014-06-24 | GSE46584 | GEO
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