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ProteomicsOlaparib based photo-affinity probes for PARP-1 detection in living cells
The poly-ADP-ribose polymerase (PARP) is a protein from the family of ADP-ribosyltransferases that catalyzes poly adenosine diphosphate ribose (ADPR) formation in order to attract the DNA repair machinery to DNA damage sites. Inhibition of PARP activity by olaparib can cause cell death which is of c...
ORGANISM(S): Homo sapiens (Human) 
2020-04-29 | PXD018661 | Pride
Olaparib  parp-1  bioorthogonal chemistry  chemical proteomics  photoaffinity probes 
ProteomicsPlasma functionalization of PCL nanofibers changes protein interactions with cells resulting in increased cell viability
The surface properties of electrospun scaffolds can greatly influence protein adsorption and thus strongly dictate cell-material interactions. In this study, we aim to investigate possible correlations between the surface properties of argon, nitrogen and ammonia/helium plasma-functionalized polycap...
ORGANISM(S): Homo sapiens (Human) 
2018-08-29 | PXD010910 | Pride
Human Synaptg2si Functionalized plasma Hff Nanofibres 
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