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Syndecan-2 was found to act as a tumor suppressor in osteosarcoma and to mediate the apoptotic response to cytotoxic agents. To determine new mechanisms that control cell survival and apoptosis in osteosarcoma cells, we aim to show target genes that are involved downstream of this proteoglycan durin...
ORGANISM(S): Homo sapiens 
To get more insight into the role of syndecan-2, we here sought to identify interaction partners of syndecan-2 in rat left ventricle. By using three different affinity purification methods combined with mass spectrometry (AP-MS) analysis, we identified 30 novel partners and 9 partners previously des...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-12-01 | PXD018942 | Pride
Gene expression analysis of hematopoietic stem cells based on Syndecan-2 surface expression
Syndecan-2 was found to act as a tumor suppressor in osteosarcoma and to mediate the apoptotic response to cytotoxic agents. To determine new mechanisms that control cell survival and apoptosis in osteosarcoma cells, we aim to show target genes that are involved downstream of this proteoglycan durin...
ORGANISM(S): Homo sapiens 
2013-09-23 | GSE19913 | GEO
Analysis of how Syndecan-2 expression identifies hematopoietic stem cells with unique gene expression profiles. We tested the hypothesis that Syndecan-2 expression enriches for hematopoietic stem cell gene expression programs. The results provide important insight into how Syndecan-2 can be used to ...
ORGANISM(S): Mus musculus 
2022-03-09 | GSE151733 | GEO
Syndecan-2 and apoptosis in osteosarcoma
VISTA is an activating receptor that binds the proteoglycan Syndecan-2 on monocytes.
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