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TranscriptomicsMDA-9/Syntenin regulates differentiation and angiogenesis programs in Head and Neck Squamous Cell Carcinoma
We identified MDA-9/Syntenin (8q12) as a key component of HNSCC differentiation and angiogenesis. Robust reduction in the expression of cyclinD1, CDK4, CTNNB1, STAT3 and PI3K were evident in MDA- 9/Syntenein depleted cells, which was reversed following MDA-9/Syntenin overexpression in immortalized o...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-57760 | biostudies-arrayexpress
TranscriptomicsSyntenin-1 is expressed in uveal melanoma and correlates with metastatic progression
Uveal melanoma is an aggressive cancer that metastasizes to the liver in about half of patients, being at that time almost always fatal. Identification of patients at high risk of metastases may provide indication for a frequent follow-up for early detection of metastases and treatment. The analysis...
ORGANISM(S): Homo sapiens 
2012-04-17 | E-GEOD-27831 | biostudies-arrayexpress
ProteomicsSyntenin inhibition impairs stroma-tumor communication in Multiple Myeloma and improves Bortezomib treatment efficiency
In multiple myeloma, the objective is to assess the impact of syntenin knockout on the secretory profile of bone marrow stromal cells using the HS-5 model.
ORGANISM(S): Homo sapiens (Human) 
2025-07-26 | PXD064458 | Pride
Lc-msms Multiple myeloma Tumor stroma communication Syntenin inhibition Secretome 
UnknownSyntenin inhibition impairs stroma-tumor communication in multiple myeloma and improves bortezomib treatment efficiency.
Not available
S-EPMC12358804 | biostudies-literature
TranscriptomicsSyntenin-1 is expressed in uveal melanoma and correlates with metastatic progression
Uveal melanoma is an aggressive cancer that metastasizes to the liver in about half of patients, being at that time almost always fatal. Identification of patients at high risk of metastases may provide indication for a frequent follow-up for early detection of metastases and treatment. The analysis...
ORGANISM(S): Homo sapiens 
2012-04-18 | GSE27831 | GEO
UnknownInhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin.
Not available
S-EPMC5240699 | biostudies-literature
UnknownPharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo.
Not available
S-EPMC7737769 | biostudies-literature
UnknownMda-9/syntenin is expressed in uveal melanoma and correlates with metastatic progression.
Not available
S-EPMC3258266 | biostudies-literature
UnknownMetabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis.
Not available
S-EPMC10757714 | biostudies-literature
UnknownSyntenin-1-mediated arthritogenicity is advanced by reprogramming RA metabolic macrophages and Th1 cells.
Not available
S-EPMC10314955 | biostudies-literature
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