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TranscriptomicsConverting Escherichia coli to a synthetic methylotroph growing solely on methanol
Methanol, being electron-rich and derivable from methane or CO2, is a potentially renewable one-carbon (C1) feedstock for microorganisms. Although the ribulose monophosphate (RuMP) cycle used by methylotrophs to assimilate methanol differs from the typical sugar metabolism by only three enzymes, tur...
ORGANISM(S): Escherichia coli 
2020-09-01 | GSE153477 | GEO
Genomics
Synthetic Methylotroph Saccharomyces cerevisiae Whole genome resequencing
PRJNA1085989 | ENA
Genomics
Synthetic Methylotroph Saccharomyces cerevisiae transcriptome profiling
PRJNA1086020 | ENA
UnknownA synthetic methylotroph achieves accelerated cell growth by alleviating transcription-replication conflicts.
Not available
S-EPMC11695965 | biostudies-literature
UnknownEvolutionary engineering of <i>Saccharomyces cerevisiae</i>: Crafting a synthetic methylotroph via self-reprogramming.
Not available
S-EPMC11661404 | biostudies-literature
UnknownImproving the Methanol Tolerance of an Escherichia coli Methylotroph via Adaptive Laboratory Evolution Enhances Synthetic Methanol Utilization.
Not available
S-EPMC7904680 | biostudies-literature
ProteomicsSynthetic Methylotrophic E. coli proteomics
To effectively use methanol derived from CO2 or methane in E. coli, it is crucial to develop a fast-growing strain that can efficiently process methanol. We successfully developed a methylotrophic E. coli strain, SM6, which has a doubling time of 3.5 hours, surpassing the growth rates of typical nat...
ORGANISM(S): Escherichia coli 
2024-04-24 | PXD051688 | Pride
Synthetic methylotroph Methanol Proteomics E. coli Synthetic biology 
TranscriptomicsExpression data from Saccharomyces cerevisiae
Reprogramming a non-methylotrophic industrial host, such as Saccharomyces cerevisiae, to a synthetic methylotroph reprents a huge challenge due to the complex regulation in yeast. Through TMC strategy together with ALE strategy, we completed a strict synthetic methylotrophic yeast that could use met...
ORGANISM(S): Saccharomyces cerevisiae 
2024-05-02 | GSE173802 | GEO
UnknownCross-Feeding of a Toxic Metabolite in a Synthetic Lignocellulose-Degrading Microbial Community.
Not available
S-EPMC7914493 | biostudies-literature
UnknownExploitation of a Type 1 Toxin-Antitoxin System as an Inducible Counter-Selective Marker for Genome Editing in the Acetogen Eubacterium limosum.
Not available
S-EPMC10223405 | biostudies-literature
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