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Construction of Synthetic Nanobody Library in Mammalian Cells by dsDNA-Based Strategies
A nanobody is an antibody fragment consisting of a single monomeric variable antigen-binding domain. Mammalian cells are ideal platforms for identifying nanobodies targeting hard-to-display transmembrane proteins and nanobodies that function as modulators of cellular phenotypes. However, the introdu...
ORGANISM(S): Homo sapiens 
2021-09-21 | GSE158906 | GEO
Tissue-penetrating nanobodies as drug-delivery vehicles have shown efficacy in treating hard-to-reach and -treat diseases. The present study reports nanobodies with application potential in the treatment of tuberculosis (TB), especially the antibiotic tolerant biofilms that form in TB granulomas. Us...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) Mycobacterium marinum 
2023-03-30 | PXD033425 | Pride
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