Systemic lupus erythematosus

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Unknown (5693)
Genomics (706)
Transcriptomics (507)
Proteomics (89)
Methylation profiling (22)
Other (18)
Genomic (16)
Metabolomics (9)
Clinical (3)

Organisms

Homo sapiens (493)
Mus musculus (195)
Andropogon gerardi (45)
Bacteria (45)
Canis lupus familiaris (45)
Cnidaria (45)
Cricetulus griseus (45)
Eukaryota (45)
Fasciola (45)
Hepatitis B virus (45)
Human betaherpesvirus 5 (45)
Madurella mycetomatis (45)
Mesocricetus auratus (45)
Bos taurus (15)
Capra hircus (8)
Oryctolagus cuniculus (7)
Gallus gallus (6)
Escherichia coli (5)
Candida albicans (3)
Rattus norvegicus (3)
Sus scrofa (3)
Homo (2)
Arabidopsis thaliana (1)
Spodoptera frugiperda (1)
Triticum aestivum (1)
unidentified plasmid (1)
Canis lupus familiaris (1)
synthetic construct (1)
Ovis aries (1)
cellular organisms (1)

Organisms

Homo sapiens (320)
Mus musculus (139)
human gut metagenome (4)
Bos taurus (2)
Cladophialophora bantiana (1)
unidentified (1)
Listeria innocua (1)
Oryctolagus cuniculus (1)
human oral metagenome (1)
human metagenome (1)
Canis lupus familiaris (1)
Listeria monocytogenes (1)
mouse gut metagenome (1)
Lactiplantibacillus plantarum (1)
Sus scrofa (1)
Homo (1)
Rattus norvegicus (1)

Repository

ENA (594)
geo (421)
biostudies-arrayexpress (209)
EGA (50)
pride (45)
dbGaP (16)
MetaboLights (9)
iProX (8)
ExpressionAtlas (4)
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jPOST (3)
EVA (2)
NODE (1)
PAXDB (1)

Tissue

Blood (10)
Cell culture (8)
Blood serum (5)
B cell (3)
Neutrophil (3)
Blood plasma (2)
Kidney (2)
Peripheral blood mononuclear cell (2)
Spleen (2)
Blood cell (1)
Blood platelet (1)
Brain (1)
Cerebrospinal fluid (1)
Endocardial cell (1)
Lymph node (1)
Macrophage (1)
Monocyte (1)
Natural killer cell (1)
Peritoneal exudate (1)
Peritoneal fluid (1)
Permanent cell line cell (1)
Platelet (1)
Urine (1)

Disease

Systemic lupus erythematosus (22)
Normal (5)
Rheumatoid arthritis (4)
Systemic scleroderma (2)
Primary antiphospholipid syndrome (1)
Microscopic Polyangiitis (1)
Sjogren's syndrome (1)
Immuno-osseus dysplasiaspondyloenchondrodysplasia (SPENCD) (1)
Cystic Fibrosis (1)
Melanoma (1)
Neoplasms (1)
Adult dermatomyositis (1)
Dermatomyositis (1)
Polymyositis (1)
Acute leukemia (1)
Disease free (1)
Inflammation (1)
Prion disease (1)
Sjogren's Syndrome (1)

Technology Type

Mass Spectrometry (45)
Shotgun proteomics (29)
Bottom-up proteomics (7)
Mass spectrometry assay (4)
Data-independent acquisition (4)
Mass spectrometry (3)
Data-dependent acquisition (3)
Illumina HiSeq 2000 (2)
NMR spectroscopy assay (2)
Affinity purification coupled with mass spectrometry proteomics (2)
MSE (2)
Illumina Genome Analyzer II (1)
DiaPASEF (1)
Gel-based experiment (1)
Mass spectrometry imaging (1)
SRM/MRM (1)
SWATH MS (1)
Top-down proteomics (1)

Instrument Platform

Illumina HiSeq 4000 (6)
NextSeq 500 (5)
Agilent 2100 Bioanalyzer (4)
Illumina NovaSeq 6000 (4)
HiSeq X Ten (3)
Q Exactive (3)
GeneChip Instrument System (2)
Affymetrix mouse gene 1.0 ST arrays (2)
NextSeq 2000 (2)
Illumina HiSeq 2500 (2)
Illumina HiSeq 2000 (2)
Nuclear Magnetic Resonance (NMR) - (2)
Liquid Chromatography MS - alternating - hilic (2)
Microbeads (1)
Ribo-Zero Gold (Illumina) (1)
Agilent SureScan High-Resolution DNA Microarray Scanner (1)
TruSeq Stranded Total RNA Library Prep Kit with Ribo-Zero Gold (Illumina) (1)
ScanArray Express HT [PerkinElmer] (1)
Illumina Genome Analyzer II (1)
N/A (1)
DNBSEQ-T7 (1)
Bio-Rad CFX96 (1)
- (1)
Q Exactive HF-X (1)
Liquid Chromatography MS - - hilic (1)
Liquid Chromatography MS - negative - reversed-phase (1)
Liquid Chromatography MS - positive - reversed-phase (1)
Gas Chromatography MS - (1)
Liquid Chromatography MS - positive - reverse-phase (1)
Liquid Chromatography MS - negative - reverse-phase (1)

Publication Date

2026 (72)
2024 (69)
2025 (56)
2022 (46)
2016 (44)
2021 (42)
2018 (42)
2014 (42)
2023 (40)
2012 (39)
2010 (32)
2020 (30)
2019 (30)
2013 (24)
2011 (24)
2015 (23)
2009 (16)
2008 (15)
2017 (12)
2007 (5)
2006 (2)

UNIPROT ID/AC

41_CANLF (1)
8ODP_CANLF (1)
9612.ENSCAFP00000000237 (1)
9612.ENSCAFP00000000343 (1)
9612.ENSCAFP00000000570 (1)
9612.ENSCAFP00000000590 (1)
9612.ENSCAFP00000000610 (1)
9612.ENSCAFP00000000777 (1)
9612.ENSCAFP00000000811 (1)
9612.ENSCAFP00000001209 (1)
9612.ENSCAFP00000001469 (1)
9612.ENSCAFP00000001485 (1)
9612.ENSCAFP00000001518 (1)
9612.ENSCAFP00000001534 (1)
9612.ENSCAFP00000001958 (1)
9612.ENSCAFP00000002082 (1)
9612.ENSCAFP00000002162 (1)
9612.ENSCAFP00000002172 (1)
9612.ENSCAFP00000002225 (1)
9612.ENSCAFP00000002253 (1)
9612.ENSCAFP00000002283 (1)
9612.ENSCAFP00000002831 (1)
9612.ENSCAFP00000003197 (1)
9612.ENSCAFP00000003199 (1)
9612.ENSCAFP00000003256 (1)
9612.ENSCAFP00000003412 (1)
9612.ENSCAFP00000003492 (1)
9612.ENSCAFP00000003711 (1)
9612.ENSCAFP00000003938 (1)
9612.ENSCAFP00000004402 (1)

CHEBI ID

CHEBI:28324 (2)
CHEBI:9532 (2)
CHEBI:28689 (2)
CHEBI:70744 (2)
CHEBI:16576 (2)
CHEBI:10072 (2)
CHEBI:17347 (2)
CHEBI:18123 (2)
CHEBI:15727 (2)
CHEBI:17196 (2)
CHEBI:16761 (2)
CHEBI:16335 (2)
CHEBI:16643 (2)
CHEBI:17895 (2)
CHEBI:18344 (2)
CHEBI:192377 (1)
CHEBI:44813 (1)
CHEBI:145832 (1)
CHEBI:145831 (1)
CHEBI:52323 (1)
CHEBI:36714 (1)
CHEBI:166843 (1)
CHEBI:191041 (1)
CHEBI:41450 (1)
CHEBI:8075 (1)
CHEBI:145830 (1)
CHEBI:42156 (1)
CHEBI:89951 (1)
CHEBI:21717 (1)
CHEBI:28319 (1)

Metabolite Name

Benzoic acid (3)
L-Asparagine (3)
L-Histidine (3)
Choline (3)
Taurine (3)
L-Proline (3)
Adenosine monophosphate (3)
Adenosine (3)
L-Valine (3)
L-Leucine (3)
L-Methionine (3)
L-Tyrosine (3)
L-Phenylalanine (3)
Guanosine-5'-diphosphate (2)
Thymidine-5'-phosphate (2)
Uridine-5'-diphosphate (2)
Guanosine-5'-monophosphate (2)
Adenosine-5'-diphosphate (2)
Nicotinamide mononucleotide (2)
Flavin adenine dinucleotide (2)
Cytidine-5'-monophosphate (2)
Thiamine pyrophosphate (2)
L-Saccharopine (2)
8-Hydroxyguanosine (2)
N-Isovaleroylglycine (2)
L-Carnosine (2)
Diphenylamine (2)
L-Norleucine (2)
2-Methylbenzoic acid (2)
Lactic acid (2)

First Public Date

2024 (83)
2026 (73)
2025 (71)
2014 (60)
2022 (50)
2021 (45)
2023 (39)
2018 (39)
2019 (33)
2020 (32)
2017 (22)
2016 (19)
2013 (14)
2015 (13)
2012 (1)

Classification

fungi (1)
bacteria (1)

Study status

Recruiting (2)
Active, not recruiting (1)

Study type

Transcription profiling by array (142)
RNA-seq of coding RNA (20)
Proteomic profiling by array (12)
Methylation profiling by array (5)
Unknown experiment type (4)
ChIP-seq (4)
Transcription profiling by RT-PCR (3)
RNA-seq of total RNA (3)
ATAC-seq (2)
Other (2)
RNA-seq of coding RNA from single cells (2)
Methylation profiling by high throughput sequencing (2)
Interventional (2)
Human - High-throughput sequencing (1)
Human - One-color microarray (1)
Capture-C (1)
Antigen profiling (1)
Comparative genomic hybridization by array (1)
MicroRNA profiling by array (1)
CUT&RUN (1)
RNA-seq of non coding RNA (1)
Observational (1)

Release Date

2022 (696)
2025 (694)
2023 (619)
2021 (587)
2024 (556)
2020 (387)
2019 (353)
2018 (321)
2017 (245)
2016 (234)
2015 (198)
2014 (185)
2012 (156)
2013 (146)
2011 (114)
2010 (108)
2026 (83)
2009 (74)
2008 (51)
2007 (30)
2006 (22)
2005 (14)
2004 (7)
2001 (7)
2000 (4)
2003 (3)
2002 (3)
1999 (3)
1998 (1)
1994 (1)

Lab affiliation

Shenzhen People’s Hospital (3)
Clinical and Diagnostic Immunology, Department Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium (2)
Scripps Research (2)
Weizmann Institute of Science (2)
1. Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, 115 27 Athens, Greece. 2. Joint Rheumatology Program, 4th Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, 124 62 Athens, Greece. (1)
Aalborg University (1)
Arkana Laboratories, Little Rock, Arkansas, USA (1)
Arthritis Research UK Career Development Fellow Institute of Aging and Chronic Disease University of Liverpool (1)
Centre Hospitalier Universitaire Vaudois, Service de Médecine Interne, BH 10-667, Rue du Bugnon 46, CH-1011 Lausanne (1)
Chinese Academy of Sciences Shanghai Institute of Materia Medica (1)
Convergence Medicine Research Center, Bio-Medical Institute of Technology, Asan Institution for Life Science, Asan Medical Center, Department of Biomedical Sciences, University of Ulsan, College of Medicine 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea (1)
Department of Analytical Chemistry and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China (1)
Department of Cellular Biology and Immunology, Lab 201, IPBLN-CSIC, Granada, Spain. (1)
Department of Cellular Biology and Immunology, Lab 201, Instituto de Parasitología y Biomedicina López-Neyra (IPBLN), Consejo Superior de Investigaciones Científicas (CSIC), Spain. (1)
Department of Clinical Sciences Lund, Section of Rheumatology, Lund University Faculty of Medicine, Lund, Skåne, Sweden (1)
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, 230032, PR China (1)
Department of General Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education (1)
Department of Medical & Molecular Genetics, King’s College London, United Kingdom (1)
Discovery Proteomics Facility Oxford (1)
Division of Allergy and Clinical immunology, Bnai-Zion Medical Center, The Rappaport Faculty of Medicine, Technion, Haifa, Israel. (1)
Head of the Curie Institute Mass Spectrometry Platform (1)
Institute of Dermatology and Department of Dermatology of the First Affiliated Hospital, Anhui Medical University, Hefei, China. (1)
Institute of Molecular Medicine The Center for Autoimmune, Musculoskeletal and Musculoskeletal Disease Feinstein Institutes for Medical Research Northwell Health 350 Community Drive Manhasset, NY 11030 (1)
Laboratory Head (1)
Laboratory of Autoimmunity and Inflammation, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation Academy of Athens, 115 27 Athens, Greece. (1)
MSAP UAR 3290 Bat C4 avenue paul langevin villeneuve d'ascq (1)
NIH/NHLBI Proteomics Core Facility (1)
Nephrology Department of Guilin No.924 Hospital, Guangxi Key Laboratory of Metabolic Diseases Research, Guilin Key laboratory of Kidney Diseases Research; Clinical Medical Research Center, The Second Clinical Medical College of Jinan University (Shenzhen People’s Hospital) (1)
Ningxia Medical University (1)
Peter A. Nigrovic, MD Chief, Division of Immunology, Boston Children’s Hospital Professor of Pediatrics and Medicine (1)

Location

United States (3)
Canada (1)

Keyword

Diabete Mellitus (1)
Sickle Cell Disease (1)
Sjogren’s Syndrome (1)
Nivolumab (1)

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Fecal Metabolomics and Potential Biomarkers for Systemic Lupus Erythematosus

The role of metabolomics in autoimmune diseases has been a rapidly expanding area in researches over the last decade, while its pathophysiologic impact on systemic lupus erythematosus (SLE) remains poorly elucidated. In this study, we analyzed the metabolic profiling of fecal samples from SLE patien...

2020-01-30 | MTBLS916 | MetaboLights

Comparative 1H-NMR Lipoprotein Profiling of Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients Highlights Disease-Specific Lipoprotein Dysregulation

Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are systemic autoimmune diseases associated with increased cardiovascular risk and metabolic alterations. We applied 1H-NMR spectroscopy to profile lipoproteins and metabolites in women with RA, SLE, and healthy controls. Both RA an...

2026-02-02 | MTBLS13820 | MetaboLights

Characteristics of steroid hormones in systemic lupus erythematosus revealed by GC/MS-based metabolic profiling

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with a remarkable predominance in female, suggesting that steroid hormones may be involved in the pathogenesis. Herein, more than 70 kinds of steroids in urine were detected by gas chromatography/mass spectrometry (GC/MS) to reve...

2023-07-28 | MTBLS7766 | MetaboLights

Transcobalamin 2 orchestrates monocyte proliferation and TLR4-driven inflammation in systemic lupus erythematosus via folate one-carbon metabolism

BACKGROUND: SLE is a complex autoimmune disease with deleterious effects on various organs. Accumulating evidence has shown abnormal vitamin B12 and one-carbon flux contribute to immune dysfunction. Transcobalamin II (TCN2) belongs to the vitamin B12-binding protein family respon...

2024-05-28 | MTBLS9136 | MetaboLights

Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4

IRF5 and STAT4 are strongly associated with human systemic lupus erythematosus (SLE). By performing chromatin immunoprecipitation-sequencing (ChIP-Seq) in human peripheral blood mononuclear cells (PBMCs), we identified more than 7000 target genes for IRF5 and STAT4 in stimulated PBMCs. Contrarily, w...

ORGANISM(S): Homo sapiens

2012-06-08 | E-GEOD-38567 | biostudies-arrayexpress

Global DNA methylation profiling of CD4+ T cells from patients with systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a chronic-relapsing autoimmune disease of incompletely understood etiology. Recent evidence strongly supports an epigenetic contribution to the pathogenesis of lupus. To understand the extent and nature of dysregulated DNA methylation in lupus T cells, we perfor...

ORGANISM(S): Homo sapiens

2011-06-10 | E-GEOD-27895 | biostudies-arrayexpress

Transcription profiling of CD14 monocytyes and CD16 neutrophils from patients with systemic lupus erythematosus

Copy number variation (CNV) has been shown to be common in regions of the genome coding for immune-related genes, and thus impacts upon polygenic autoimmunity. Low copy number of FCGR3B has recently been associated with systemic lupus erythematosus (SLE). FcγRIIIb is a glycosylphosphatidylino...

ORGANISM(S): Homo sapiens

2008-10-02 | E-TABM-463 | biostudies-arrayexpress

Transcription profiling of human systemic lupus erythematosus patients to develop a transcriptional indicator of disease progression

Transcriptional modules were used as a basis for the selection of biomarkers and the development of a multivariate transcriptional indicator of disease progression in patients with systemic lupus erythematosus. Experiment Overall Design: The proposed biomarker-selection strategy relies on modules ...

ORGANISM(S): Homo sapiens

2008-10-01 | E-GEOD-11909 | biostudies-arrayexpress

Expression data from human healthy and lupus EPCs/CACs, and healthy CD133+ bone marrow EPCs

Systemic lupus erythematosus (SLE) is characterized by increased vascular risk due to premature atherosclerosis independent of traditional risk factors. We previously proposed that interferon-α plays a crucial role in premature vascular damage in SLE. IFN-α alters the balance between endothelial cel...

ORGANISM(S): Homo sapiens

2011-04-13 | E-GEOD-23203 | biostudies-arrayexpress

Systemic lupus erythematosus

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

2014-06-03 | E-GEOD-46923 | biostudies-arrayexpress

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