Sort   by:  
 Page size 
MetabolomicsMetabolomic approaches to dissect dysregulated metabolism in the progression of pre-diabetes to T2DM

Most of pre-diabetes were eventually progress to diabetes, thereby profiling of prediabetic metabolic disorders may be an effective targeted preventive measure. We aimed to elucidate internal motivation of the progression of pre-diabetes to type 2 diabetes mellitus (T2DM) from a metabolic perspec...

2024-04-29 | MTBLS8644 | MetaboLights
MetabolomicsZhaqu Compound Improves Glucose and Lipid Metabolism in T2DM with MASLD by Modulating Gut Microbiota and PPARγ

Type 2 diabetes mellitus (T2DM) with metabolic syndrome-associated steatohepatitis (MASLD) is a complex metabolic comorbidity characterized by hyperglycemia, pancreatic β-cell dysfunction, and hepatic lipid metabolism disorders, in which gut microbiota dysbiosis and abnormal PPARγ signaling play ...

2026-02-25 | MTBLS13933 | MetaboLights
MetabolomicsEffects of herb DG and KK01 on Type 2 Diabetes Mellitus (T2DM) through Lipidomics
Not available
ORGANISM(S): Mus musculus 
ST000530 | MetabolomicsWorkbench
ProteomicsIdentification of Novel Auto-antibodies in Type 1 Diabetic Patients using a High-density Protein Microarray
Type 1 diabetes mellitus (T1DM) results from immune mediated destruction of pancreatic beta cells. However, clinical and immunologic phenotypes of T1DM are variable. Several auto-antibodies including GADA, IA-2A, and ZnT8A, were identified in T1DM, but the prevalence of these auto-antibodies varied ...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-50866 | biostudies-arrayexpress
TranscriptomicsPreadipocytes of T2DM patients display an intrinsic gene expression profile of decreased differentiation capacity
Insulin resistance and Type 2 Diabetes Mellitus (T2DM) are associated with increased adipocyte size, altered secretory pattern and decreased differentiation of preadipocytes. To identify the underlying molecular processes in preadipocytes of T2DM patients that are a characteristic of the development...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-15790 | biostudies-arrayexpress
ProteomicsRetinal proteomic study of high-fat diet-induced T2DM model: exploring the interventional targets of nonproliferative diabetic retinopathy
Objective: This study aims to establish a T2DM rat model consistent with the natural history of the disease, and apply TMT proteomics technology to analyze the retina to reveal the pathogenic mechanism of NPDR and search for new targets for NPDR intervention. Methods: Six-week-old SD male rats were ...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-05-07 | PXD056236 | Pride
Diabetes retinopathy  rat model of t2dm  tmt proteomics  fatty acid metabolism 
ProteomicsA mitochondrial proteome profile of type 2 diabetes mellitus in skeletal muscles
The goal of the project is to understand the mitochondrial proteome profiles related to T2DM. We performed comprehensive proteome profiling of mitochondria isolated from skeletal muscles in nine T2DM patients and nine control subjects with normal glucose tolerance (NGT).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-13 | MSV000083560 | MassIVE
ProteomicsProteomics analysis reveals insights into the role of lipid metabolism in T2DM-related sarcopenia
Sarcopenia has been recognized as an emerging complication of type 2 diabetes mellitus (T2DM). Currently, the pathogenesis of T2DM-related sarcopenia remains unclear. The aim of this study was to investigate the molecular mechanisms and potential therapeutic targets for T2DM-related sarcopenia. In t...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD051462 | Pride
Proteomics Lipid metabolism T2dm-related sarcopenia Fatty acid oxidation Diabetes mellitus Sarcopenia 
GenomicsFecal samples from T2DM patients
Fecal samples from T2DM patients
PRJNA1238196 | ENA
TranscriptomicsCorrelation of Candidate Genetic Variations for Susceptibility and Risk Assessment of Type 2 Diabetes Mellitus and its Related Medical Conditions among Filipinos (DM2)
Various studies have established the role of genetics in the development of type 2 diabetes mellitus (T2DM) across population groups with a reported heritability of 30–70%. These studies highlight the effect of interethnic variability in genetic susceptibility and risk for complications of T2DM. The...
ORGANISM(S): Homo sapiens 
2026-09-01 | E-MTAB-17412 | biostudies-arrayexpress
Sort   by:  
 Page size