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TranscriptomicsSpatial organisation of the X inactivation center
We report the application of Chromosome Conformation Capture Carbon-copy (5C) to a 4.5 Mb stretch of the mouse X chromosome encompassing the X inactivation center locus. We uncover a series of discrete 200kb-1Mb topologically associating domains (TADs). These align with several domain-wide epigenomi...
ORGANISM(S): Mus musculus 
2012-04-11 | E-GEOD-35721 | biostudies-arrayexpress
TranscriptomicsDistinct structural transitions of chromatin topological domains coordinate hormone-induced gene regulation
The three-dimensional (3D) organization of the genome within the cell nucleus contributes to cell-specific gene expression in different cell types1. High-throughput 3CM-bM-^@M-^Sderived methods have revealed that the genome is segmented into contiguous topologically associating domains (TADs), which...
ORGANISM(S): Homo sapiens 
2014-10-06 | E-GEOD-53463 | biostudies-arrayexpress
UnknownMaking sense of the linear genome, gene function and TADs.
Not available
S-EPMC8800309 | biostudies-literature
UnknownOral microbiome contributes to the failure of orthodontic temporary anchorage devices (TADs).
Not available
S-EPMC9844000 | biostudies-literature
UnknownRegulation of single-cell genome organization into TADs and chromatin nanodomains.
Not available
S-EPMC7610512 | biostudies-literature
GenomicsMCM complexes are barriers that restrict loops and TADs
MCM complexes are barriers that restrict loops and TADs
PRJNA656247 | ENA
UnknownBINDER achieves accurate identification of hierarchical TADs by comprehensively characterizing consensus TAD boundaries.
Not available
S-EPMC12047538 | biostudies-literature
UnknownHi-TrAC detects active sub-TADs and reveals internal organizations of super-enhancers.
Not available
S-EPMC10325921 | biostudies-literature
GenomicsPromoter-enhancer communication occurs primarily within Gene Unit Sub-TADs (GUSTs)
Promoter-enhancer communication occurs primarily within Gene Unit Sub-TADs (GUSTs)
PRJNA474608 | ENA
UnknownTADs are 3D structural units of higher-order chromosome organization in Drosophila.
Not available
S-EPMC5829972 | biostudies-literature
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