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TranscriptomicsTranscriptional networks controlling the cell cycle
In this work, we use RNAi and subsequent RNA isolation and Affymetrix Expression array analysis to map the genome-wide transcriptional targets of 107 of the strongest cell cycle regulators. Drosophila S2 cells were used with RNAi target gene knockdown compared to control (GFP dsRNA). RMA normalized...
ORGANISM(S): Drosophila melanogaster 
2012-06-30 | E-MTAB-453 | biostudies-arrayexpress
TranscriptomicsExpression profiling of MCF7 cells upon nutlin3a treatment
The tumor suppressor p53 can induce various biological responses. Yet it is not clear whether it is p53 in vivo promoter selectivity that triggers different transcription programs leading to different outcomes. Our analysis of genome-wide chromatin occupancy by p53 using ChIP-seq (deposited in Seque...
ORGANISM(S): Homo sapiens 
2012-09-07 | E-GEOD-30183 | biostudies-arrayexpress
Genomicsena-DATASET-ICR-PTGT-05-02-2015-11:21:41:591-6 - samples
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci.
EGAD00001001243 | EGA
GenomicsCapture Hi-C identifies the chromatin interactome of colorectal cancer risk loci
Multiple regulatory elements distant to their targets on the linear genome can influence the expression of a single gene through chromatin looping. Chromosome conformation capture implemented in Hi-C allows for genome-wide agnostic characterization of chromatin contacts. However, detection of functi...
EGAS00001001085 | EGA
GenomicsMolecular and Population Genetics (MPG) research at ICR DAC agreement
Data Access Committee EGAC00001000303
EGAC00001000303 | EGA
ProteomicsCRISPR-Assisted Detection of RNA-Protein Interactions in Living Cells
We develop a CRISPR-Assisted RNA-Protein Interaction Detection method (CARPID), which leverages CRISPR/CasRx-based RNA targeting and proximity labeling to identify binding proteins of specific lncRNA in the native cellular context.
ORGANISM(S): Homo Sapiens 
PXD015702 |
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