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MetabolomicsWhole blood metabolomics of dementia patients reveal classes of disease-linked metabolites

Dementia is caused by factors that damage neurons. We quantified small molecular markers in whole blood of dementia patients, using non-targeted liquid chromatography-mass spectroscopy (LC-MS). Thirty-three metabolites, classified into 5 groups (A-E), differed significantly in dementia patients, ...

2021-07-06 | MTBLS2109 | MetaboLights
UnknownPlasma pharmacokinetics and synovial concentrations of S-flurbiprofen plaster in humans.
Not available
S-EPMC4701782 | biostudies-literature
TranscriptomicsTranscription profiling of human multiple myeloma cells ( MM1.S) cells with control or beta-catenin knockdown.
MM1.S cells stably transduced with control or beta-catenin shRNA were established. Total RNA was isolated from 5x 10^6 cells of each in triplicate. Experiment Overall Design: Comparative gene expression profiling in multiple myeloma.
ORGANISM(S): Homo sapiens 
2009-09-15 | E-GEOD-17385 | biostudies-arrayexpress
UnknownA segmental duplication encompassing S-haplotype triggers pollen-part self-compatibility in Japanese pear (Pyrus pyrifolia).
Not available
S-EPMC3890579 | biostudies-literature
UnknownMLPK function is not required for self-incompatibility in the S29 haplotype of Brassica rapa L.
Not available
S-EPMC10363064 | biostudies-literature
MetabolomicsHuman age-declined saliva metabolic markers determined by LC-MS

Metabolites in human biofluids reflect individual physiological body states influenced by various factors. Using liquid chromatography-mass spectrometry (LC-MS), we conducted non-targeted, non-invasive, comprehensive metabolomics using saliva of 27 healthy volunteers in Okinawa, consisting of 13 ...

2021-02-11 | MTBLS2108 | MetaboLights
UnknownEpstein-Barr virus BGLF4 kinase retards cellular S-phase progression and induces chromosomal abnormality.
Not available
S-EPMC3387188 | biostudies-literature
UnknownMapping of a responsible region for sex reversal upstream of Sox9 by production of mice with serial deletion in a genomic locus.
Not available
S-EPMC6269501 | biostudies-literature
MetabolomicsReduced uremic metabolites are prominent feature of sarcopenia, distinct from antioxidative markers for frailty

Due to global aging, frailty and sarcopenia are increasing. Sarcopenia is defined as loss of volume and strength of skeletal muscle in elderlies, while frailty involves multiple domains of aging-related dysfunction, impaired cognition, hypomobility and decreased social activity. However, little i...

2022-10-19 | MTBLS3341 | MetaboLights
UnknownLess necessity of adjuvant S-1 treatment in non-monarchE-eligible patients.
Not available
S-EPMC10315737 | biostudies-literature
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