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TranscriptomicsTranscription profiling of Arabdiopsis plants over-expressing MKK3DD or MKK4DD to identify genes acting downstream of MAP kinase kinase
To identify genes acting downstream of MAP kinase kinase, and thus map its signal, we used the steroid-inducible overexpression system. The constitutive active form MKK3 (MKK3DD) or MKK4 (MKK4DD) was cloned into the glucocorticoid-inducible vector pTA7002 and transformed using Agrobacterium method i...
ORGANISM(S): Arabidopsis thaliana 
2007-05-11 | E-MEXP-827 | biostudies-arrayexpress
TranscriptomicsExpression data from common myeloid progenitor cells (CMP) of C57BL6 mouse
Common myeloid progenitor cells from murine bone marrow were sorted according to ROS content using FACS with H2-DCFDA staining. We compared gene expression profile between CMP with low-ROS levels and those with high-ROS levels. We analysed function of ROS in differentiation step from CMP to MEP.
ORGANISM(S): Mus musculus 
2014-05-09 | E-GEOD-57469 | biostudies-arrayexpress
TranscriptomicsArray CGH data of A. oryzae strains bearing targeted tandem chromosomal duplications
We here describe the first successful construction of a targeted tandem duplication of a large chromosomal segment in Aspergillus oryzae. The targeted tandem chromosomal duplication was achieved by using strains that had 5M-bM-^@M-^YM-NM-^TpyrG upstream of the region targeted for tandem chromosomal ...
ORGANISM(S): Aspergillus oryzae RIB40 
2014-06-30 | E-GEOD-57246 | biostudies-arrayexpress
TranscriptomicsIdentification of mir-342-3p functionally associated with transcriptional activity of MYC in lung cancer [cell culture]
Accumulating evidence indicates that altered miRNA expression is crucially involved in lung cancer development, but only little has been elucidated about how MYC, an archetypical oncogene, is regulated by miRNAs, especially through a mechanism involving the MYC cofactor(s). In this study, we aimed a...
ORGANISM(S): Homo sapiens 
2016-01-06 | E-GEOD-66758 | biostudies-arrayexpress
TranscriptomicsIdentification of mir-342-3p functionally associated with transcriptional activity of MYC in lung cancer [patients]
Accumulating evidence indicates that altered miRNA expression is crucially involved in lung cancer development, but only little has been elucidated about how MYC, an archetypical oncogene, is regulated by miRNAs, especially through a mechanism involving the MYC cofactor(s). In this study, we aimed a...
ORGANISM(S): Homo sapiens 
2016-01-06 | E-GEOD-66759 | biostudies-arrayexpress
Genomicsc206f97a-4770-4337-a7bd-0bf63eede603 - samples
Whole-exome sequencing dataset for the Australian Ovarian Cancer Study (AOCS) and The Jikei University School of Medicine (JIKEI) ovarian clear cell carcinoma (OCCC) clinical outliers project, representing 10 donors. Consists of 20 fastq files: one normal and one tumour from each patient.
EGAD00001006004 | EGA
GenomicsWhole-exome sequencing of ovarian clear cell carcinoma in clinical outliers
Whole-exome sequencing dataset for the Australian Ovarian Cancer Study (AOCS) and The Jikei University School of Medicine (JIKEI) ovarian clear cell carcinoma (OCCC) clinical outliers project, representing 10 donors. Although OCCC are commonly resistant to platinum based chemotherapy, good clinical ...
EGAS00001004248 | EGA
GenomicsPeter MacCallum Cancer Centre Research Data Access Committee
Data Access Committee EGAC00001001500
EGAC00001001500 | EGA
TranscriptomicsTranscription profiling of mouse wild-type, TBK1, IKKi(Ikbke), or TBK1 IKKi doubly deficient embryonic fibroblats to elucidate how TBK1 and/or IKKi mediates B-DNA-mediated innate immune responses
B-DNA-induced gene expression profile in wild-type, TBK1, IKKi(Ikbke), or TBK1 IKKi doubly deficient embryonic fibroblats; to elucidate how TBK1 and/or IKKi mediates B-DNA-mediated innate immune responses. Experiment Overall Design: Total RNA was extracted from embryonic fibroblats transfected for 4...
ORGANISM(S): Mus musculus 
2007-12-07 | E-GEOD-4171 | biostudies-arrayexpress
TranscriptomicsExpression data (U133 Plus 2.0) from fibroblast like synoviocytes from patients with rheumatoid arthritis (RA-FLS) stimulated by DcR3
Decoy receptor 3 (DcR3), a member of the tumor necrosis factor receptor (TNFR) superfamily, competitively binds and inhibits members of the TNF family, including Fas ligand (FasL), LIGHT, and TL1A. DcR3 was recently reported not only to act as a decoy receptor for these TNFRs but also to play a role...
ORGANISM(S): Homo sapiens 
2013-04-02 | E-GEOD-45665 | biostudies-arrayexpress
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