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ProteomicsLongitudinal serum proteome analysis in COVID-19
COVID-19 is associated with endotheliopathy and coagulopathy, potentially leading to multi-organ failure. However, the direct mechanisms by which SARS-CoV-2 infection leads to endothelial damage are unclear. Here we developed an infection-competent human vascular organoid from pluripotent stem cells...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD044386 | Pride
Sars-cov-2  endotheliopathy  complement 
TranscriptomicsVascularised and functional human liver from an iPSC-derived organ bud transplant
Critical shortage of donor organs for treating end-stage organ failure highlights the urgent need for generating organs from induced pluripotent stem cells (hiPSCs). Despite many reports describing functional cell differentiation, no studies have succeeded in generating a three-dimensional vasculari...
ORGANISM(S): Mus musculus 
2013-07-01 | E-GEOD-46631 | biostudies-arrayexpress
TranscriptomicsVascularized And Complex Organ Buds From Diverse Tissues Via Mesenchymal Cell-Driven Condensation
Here, we demonstrate a generalized method for organ bud formation from diverse tissues by combining pluripotent stem cell-derived tissue-specific progenitors or relevant tissue samples with endothelial cells and mesenchymal stem cells (MSCs). The MSCs initiated condensation within these heterotypic ...
ORGANISM(S): Mus musculus 
2015-07-01 | E-GEOD-66454 | biostudies-arrayexpress
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