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The fungal pathogen Colletotrichum higginsianum secretes effector proteins during infection of Arabidopsis. To explore the host processes perturbed by the effector candidate ChEC108 in host plants, transgenic Arabidopsis lines were generated to express AtUBQ10pro:ChEC108-eGFP or AtUBQ10pro:ChEC108^D...
ORGANISM(S): Arabidopsis thaliana 
We are exploring the molecular pathways activated during lymphoid transformation with the long term goal of developing better therapies. Our focus is the HMGA1a oncogene because our studies indicate that it plays an important role in aggressive human lymphoid leukemia and lymphoma. We have developed...
ORGANISM(S): Mus musculus 
We investigated genome-wide DNA methylation of NeuN+ and NeuN- fractions in three brain regions using comprehensive high throughput arrays for relative methylation (CHARM). We isolated genomic DNA from cell-sorted post-mortem brains using NeuN antibody and hybridized to Nimblegen microarrays (091020...
ORGANISM(S): Homo sapiens 
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