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TranscriptomicsInteraction network of Talin-1 in promoting hepatocellular carcinoma progression
Talin-1, a macromolecular cytoskeletal protein, promotes hepatocellular carcinoma (HCC) progression. However the underlying mechanism of Talin-1 in HCC remains unclear. Analysis of the gene expression profiles of normal control HCC cell (MHCC-97L) and knockdown Talin-1 HCC cells (sh-Talin-1 MHCC-97L...
ORGANISM(S): Homo sapiens 
2016-12-31 | GSE86062 | GEO
GenomicsNuclear Talin-1 Provides a Bridge Between Cell Adhesion and Gene Expression
Nuclear Talin-1 Provides a Bridge Between Cell Adhesion and Gene Expression
PRJNA814198 | ENA
GenomicsHomo sapiens
Interaction network of Talin-1 in promoting hepatocellular carcinoma progression
PRJNA340158 | ENA
UnknownDe novo talin-1 variant L353F connects multifaceted clinical symptoms to alterations in talin-1 function.
Not available
S-EPMC12599238 | biostudies-literature
ProteomicsCellular stiffness sensing through talin 1 in tissue mechanical homeostasis
Tissue mechanical homeostasis, the concept that cells sense mechanical properties and alter rates of ECM synthesis, assembly and degradation, is of broad interest in biology and medicine, but there is little direct support or insight into mechanisms. Tissue mechanical properties such as elasticity a...
ORGANISM(S): Homo sapiens (Human) 
2024-07-16 | PXD041630 | Pride
Focal adhesions Stiffness-sensing Mechanical homeostasis Extra-cellular matrix Talin 
UnknownTalin-1 interaction network promotes hepatocellular carcinoma progression.
Not available
S-EPMC5355072 | biostudies-literature
ProteomicsTalin force coupling underlies eukaryotic cell-substrate adhesion
Integrin-mediated cell adhesion and mechanotransduction are considered key innovations in animal evolution, enabling a specific and physically robust attachment of cells to the extracellular environment. Here, we show that this type of cell adhesion is a specification of an evolutionary conserved fo...
ORGANISM(S): Homo sapiens (Human) Dictyostelium discoideum (Slime mold) 
2025-11-21 | PXD062078 | Pride
Mechanotransduction Mass spectrometry Evolution Talin Adhesion Dictyostelium Integrin 
UnknownTalin-1 is the principal platelet Rap1 effector of integrin activation.
Not available
S-EPMC7472713 | biostudies-literature
UnknownExpression of Talin-1 in endometriosis and its possible role in pathogenesis.
Not available
S-EPMC7942010 | biostudies-literature
UnknownDistinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation.
Not available
S-EPMC3359742 | biostudies-literature
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