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MicroRNA expression levels in the lymphoblastic cells of prostate cancer patients and their healthy brothers from HPCX1 linked prostate cancer families were analyzed to trace variants that might alter miRNA expression and explain partly an inherited genetic predisposion to prostate cancer. MicroRN...
ORGANISM(S): Homo sapiens 
miRNA expression profiling in 6 prostate cancer cell lines, 9 prostate cancer xenografts, and 13 clinical prostate tumor samples
ORGANISM(S): Homo sapiens 
Androgen receptor (AR) is overexpressed in the majority of castration-resistant prostate cancers (CRPCs). Our goal was to study the effect of AR overexpression on the chromatin binding of the receptor and to identify AR target genes that may be important in the emergence of CRPC. We have established...
ORGANISM(S): Homo sapiens 
In this study, nonsense-mediated mRNA decay (NMD) inhibition was used for the discovery of truncating mutations. Six prostate cancer (PRCA) patients and their healthy brothers were selected from a group of HPCX1-linked families. mRNA was isolated from their lymphoblastic cells after pharmacological ...
ORGANISM(S): Homo sapiens 
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