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GenomicsIRF8-induced monocyte differentiation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-01-24 | E-GEOD-38825 | biostudies-arrayexpress
TranscriptomicsGene expression analyses in IRF8-induced monocyte differentiation
To understand the differentiation program in monocyte/macrophage differentiation, we performed ChIP-seq for IRF8 and H3K4me1 together with gene expression profiling during IRF8-induced monocyte differentiation. Both promoter-proximal and -distal binding of IRF8 associated with induction of the genes...
ORGANISM(S): Mus musculus 
2013-01-24 | E-GEOD-38810 | biostudies-arrayexpress
UnknownGenome-based analysis of non-ribosomal peptide synthetase and type-I polyketide synthase gene clusters in all type strains of the genus Herbidospora.
Not available
S-EPMC4599437 | biostudies-literature
GenomicsAnalysis of TF binding sites and histone modification in IRF8-induced monocyte differentiation
Chromatins were prepared from myeloid progenitor cell line Tot2 cells transduced with retrovirus for control MSCV or MSCV-IRF8. Chromatin immunoprecipitation (ChIP) was carried out by using anti-IRF8 antibody, anti-PU.1 antibody or anti-histone H3K4me1 antibody. ChIP-Seq peaks were identified using ...
ORGANISM(S): Mus musculus 
2013-01-24 | E-GEOD-38824 | biostudies-arrayexpress
UnknownDown-regulation of vascular GLP-1 receptor expression in human subjects with obesity.
Not available
S-EPMC6045606 | biostudies-literature
TranscriptomicsGene epxression profiling in murine bone marrow Lin- cells transduced with BCR-ABL and/or IRF8 followed by Flt3L culture for 5 days
To understand the effect of BCR-ABL and IRF8 on gene expression pattern during in vitro dendritic cell differentiation, microarry analysis was performed. Murine bone marrow Lin- cells were transduced with retroviruses carrying human BCR-ABL cDNA and/or mouse Irf8 cDNA, and then cultured with Flt3L f...
ORGANISM(S): Mus musculus 
2013-11-15 | E-GEOD-44920 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in wild-type, Irf5-KO, Lyn-KO and Lyn/Irf5-DKO BMDCs unstimulated or stimulated with CpG-B ODN
To characterize the relationship between IRF5 and Lyn in innate immune responses at a genome-wide scale, we performed gene expression microarray analysis for wild-type (WT), Irf5-KO, Lyn-KO and Lyn/Irf5-DKO bone marrow-derived dendritic cells (BMDCs) with or without 6 h-stimulation with 150 nM CpG-B...
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-63014 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in murine monocyte-dendritic cell progenitors (MDPs), common monocyte progenitors (cMoPs) and 32Dcl.3 cells transduced with C/EBPalpha and/or IRF8
To understand the mechanism by which IRF8 inhibits neutrophil differentiation Murine bone marrow MDPs and cMoPs were isolated by cell sorting from wild-type or Irf8 deficient mice. 32Dcl.3 cells were transduced with retroviruses carrying murine C/EBPalpha cDNA and/or murine Irf8 cDNA. Two independe...
ORGANISM(S): Mus musculus 
2014-08-26 | E-GEOD-50052 | biostudies-arrayexpress
TranscriptomicsGene epxression profiling in murine Flt3+ granulocyte progenitors (Flt3+ GPs) and Flt3- granulocyte progenitors (Flt3- GPs)
To understand the mechanism by which IRF8 promotes basophil differentiation Murine bone marrow Flt3+ GPs and Flt3- GPs were isolated by cell sorting from wild-type or Irf8 deficient mice. Two independent experiments were performed.
ORGANISM(S): Mus musculus 
2014-11-17 | E-GEOD-54887 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing of murine lung in steady state, after IL-33 treatment or HDM treatment
Single cell RNA sequencing of the lung in steady state, after 1 or 3 doses of IL-33 or after HDM treatment Exp1: steady state lung cells (both CD45- as CD45+) from 4 untreated mice. Cells from distinct replicates are labeled with unique HTO barcodes. Exp2: lung cells (both CD45- as CD45+) from 2 mi...
ORGANISM(S): Mus musculus 
2025-12-12 | E-MTAB-16099 | biostudies-arrayexpress
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