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UnknownClinical relevance of PD-1 positive CD8 T-cells in gastric cancer.
Not available
S-EPMC10115710 | biostudies-literature
UnknownTargeting mTOR signaling overcomes acquired resistance to combined BRAF and MEK inhibition in BRAF-mutant melanoma.
Not available
S-EPMC8445818 | biostudies-literature
ProteomicsIntegrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non-functioning pituitary adenoma
Pituitary adenomas constitute 10 to 25% of intracranial tumors, rendering them one of the most prevalent types of brain tumors. While the majority of pituitary adenomas are benign, ~35% exhibit invasive behavior. Compared with their non-invasive counterparts, invasive pituitary adenomas are more cha...
ORGANISM(S): Homo Sapiens 
2025-12-09 | PXD071754 |
ProteomicsDiscovery of a cooperative mode of inhibiting RIPK1 kinase
By using Limited Proteolysis-Mass Spectrometry (LiP-MS) and Hydrogen Deuterium Exchange-Mass Spectrometry (HDX-MS) analysis, we identified the binding pocket of Nec-34 in RIPK1 kinase domain. This newly identified binding pocket of Nec-34 is distinct from distinct from that of Nec-1s.
ORGANISM(S): Homo Sapiens 
2021-03-07 | PXD024560 |
ProteomicsDiscovery of a cooperative mode of inhibiting RIPK1
We identified a peptide of RIPK1 binding with compound Nec-34
ORGANISM(S): Homo Sapiens 
2021-03-04 | PXD024534 |
ProteomicsR406 binding site on TAK1 identified by MS
We identified of R406 and its pro-drug R788 for the treatment of cancer by inducing necroptosis.
ORGANISM(S): Homo Sapiens 
PXD044897 |
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