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TranscriptomicsRNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients
Through RNA sequencing of CD4+ Tmemory/effector cells derived from the synovium of JIA patients and healthy controls, we analyzed the JIA gene expression signature. Treatment of autoinflammatory site-derived patient T cells with the BET-inhibitor JQ1 inhibited immune-related super-enhancers and pref...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-GEOD-71595 | biostudies-arrayexpress
GenomicsJBP1-seq: a fast and efficient method for genome-wide profiling of 5hmC
We developed a novel approach, J-binding protein 1 sequencing (JBP1-seq), that combines the benefits of an improved recombinant JBP1 protein, Nextera-based library construction, and nextgeneration sequencing (NGS) for genome-wide profiling of 5-hydroxymethylcytosine (5hmC). Compared with the orig...
ORGANISM(S): Homo sapiens 
2014-11-26 | E-GEOD-61193 | biostudies-arrayexpress
UnknownFibrinogen to HDL-Cholesterol ratio as a predictor of mortality risk in patients with acute myocardial infarction.
Not available
S-EPMC10962130 | biostudies-literature
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
UnknownA single-cell V(D)J sequencing dataset of peripheral blood cells in  multibacillary leprosy.
Not available
S-EPMC12290026 | biostudies-literature
UnknownA new method to investigate the catalytic mechanism of YhdE pyrophosphatase by using a pyrophosphate fluorescence probe.
Not available
S-EPMC5557916 | biostudies-literature
UnknownGenomic characterization and pathogenicity analysis of a porcine deltacoronavirus strain isolated in western China.
Not available
S-EPMC9419129 | biostudies-literature
MetabolomicsPu-erh tea and theabrownin ameliorate metabolic syndrome in mice via potential microbiota-gut-liver-brain interactions
Metabolic syndrome (MS) is a common metabolic disorder characterized by obesity, insulin resistance, cardiovascular disease and gut microbiota dysbiosis. Pu-erh tea and its ingredient theabrownin have known functions on the reduction of body weight gain and fat accumulation. However, few studies sys...
2024-09-25 | MTBLS2594 | MetaboLights
UnknownAstragalus mongholicus bunge and panax notoginseng formula (A&P) improves renal fibrosis in UUO mice via inhibiting the long non-coding RNA A330074K22Rik and downregulating ferroptosis signaling.
Not available
S-EPMC11264518 | biostudies-literature
UnknownPhytoestrogen-derived multifunctional ligands for targeted therapy of breast cancer.
Not available
S-EPMC10425851 | biostudies-literature
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