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To elucidate the fundamental molecular mechanisms responsible for multistep hepatotumorigenesis, this study investigated genes that were upregulated in a stepwise manner from the naïve liver condition through to chronic oxidative stress-induced hepatitis and liver tumor by time-series microarray ana...
ORGANISM(S): Rattus norvegicus 
The mammalian Y chromosome plays a critical role in spermatogenesis. However, the exact functions of each gene in the Y chromosome have not been completely elucidated, partly owing to difficulties in gene targeting analysis of the Y chromosome. Zfy was first proposed to be a sex determination factor...
ORGANISM(S): Mus <mouse, Genus> (ncbitaxon:10088) 
2016-11-24 | MSV000080355 | MassIVE
Hepatocyte nuclear factor-4α (HNF4α, NR2A1) is a nuclear receptor which has a critical role in hepatocyte differentiation and the maintenance of homeostasis in the adult liver. However, a detailed understanding of native HNF4α in the steady state remains to be elucidated. Here we report the native H...
ORGANISM(S): Homo sapiens 
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