Sort   by:  
 Page size 
MetabolomicsRegulatory T cells promote endurance exercise adaptation by shielding muscle mitochondria from damage

Exercise enhances physical performance and reduces the risk of many disorders such as cardiovascular disease, type 2 diabetes, dementia and cancer. Exercise characteristically incites an inflammatory response, notably in skeletal muscles. While some effector mechanisms have been identified, regul...

2023-10-10 | MTBLS8391 | MetaboLights
TranscriptomicsComparison of expression profiles of Foxp3(+)epigenetics(-) T cells, Foxp3(-)epigenetics(+) T cells, and Foxp3(+)epigenetics(+) T cells
Analysis of Foxp3(+)epigenetics(-) T cells, Foxp3(-)epigenetics(+) T cells, and Foxp3(+)epigenetics(+) T cells. Results indicate regulatory T cell (Treg) ontogenesis requires two independent processes, expression of the transcription factor Foxp3 and establishment of Treg epigenetic programs induced...
ORGANISM(S): Mus musculus 
2012-11-05 | E-GEOD-25252 | biostudies-arrayexpress
TranscriptomicsIL-27, PXN, CXCR4, GZMA, PRF1 and Foxp3 genes are differentially expressed in CD4+ T cells of HTLV-1-infected individuals.
HTLV-1 preferentially infects CD4+ T cells and these cells play a central role in HTLV-1 infection. In this study, we investigated the global gene expression profile of circulating CD4+ T cells from distinct clinical status of HTLV-1-infected individuals in regard to Tax expression levels. CD4+ T ce...
ORGANISM(S): Homo sapiens 
2013-06-01 | E-GEOD-38537 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3
Differentiation of naive CD4 T cells into type 2 helper (Th2) cells is accompanied by chromatin remodeling and increased expression of a set of Th2-specific genes including those encoding Th2 cytokines. IL-4-mediated STAT6 activation induces high levels of transcription of GATA3, a master regulator...
ORGANISM(S): Mus musculus 
2011-03-31 | E-GEOD-28292 | biostudies-arrayexpress
TranscriptomicsDifferentiating i-Mixl1 mESCs cultured in the presence or absence of Doxycycline
We profiled gene expression changes in differentiating i-Mixl1 ES cells(Willey, Ayuso-Sacido et al., 2006, Blood 107(8): 3122-3130) cultured in the presence or absence of Doxycycline (DOX, 0.1 ug/ml, 3 replicates per treatment/time point). Total RNA was isolated from EBs harvested at day 2, 3 and ...
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-40703 | biostudies-arrayexpress
TranscriptomicsInterleukin-27 priming of T cells controls Interleukin-17-production in trans via induction of Programmed cell death ligand 1
Interleukin (IL)-27 is a key immunosuppressive cytokine that counters T helper 17 (Th17) cell-mediated pathology. To identify mechanisms by which IL-27 might exert its immunosuppressive effect, we analyzed genes in T cells rapidly induced by IL-27. We found that IL-27 priming of naïve T cells upregu...
ORGANISM(S): Mus musculus 
2012-06-30 | E-GEOD-38375 | biostudies-arrayexpress
UnknownInvolvement of lncRNA IL21-AS1 in interleukin-2 and T follicular regulatory cell activation in systemic lupus erythematosus.
Not available
S-EPMC8665514 | biostudies-literature
UnknownMice deficient in the axonemal protein Tektin-t exhibit male infertility and immotile-cilium syndrome due to impaired inner arm dynein function.
Not available
S-EPMC515054 | biostudies-literature
UnknownUp Scalable Full Colour Plasmonic Pixels with Controllable Hue, Brightness and Saturation.
Not available
S-EPMC5430921 | biostudies-literature
UnknownAssociation of peripheral CD8+ T cell activation with disease activity and treatment resistance in systemic lupus erythematosus.
Not available
S-EPMC11865784 | biostudies-literature
Sort   by:  
 Page size