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TranscriptomicsCritically ill patients with either gram-positive sepsis or gram-negative sepsis
Objective: It is unclear whether the host response of gram-positive sepsis differs from gram-negative sepsis at a transcriptome level. Using microarray technology, we compared the gene-expression profiles of gram-positive sepsis and gram-negative sepsis in critically ill patients. Design: A pros...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-6535 | biostudies-arrayexpress
TranscriptomicsWhole blood transcriptome of survivors and nonsurvivors of sepsis
There is currently no reliable tool available to measure immune dysfunction in septic patients in the clinical setting. This proof-of-concept study assesses the potential of gene expression profiling of whole blood as a tool to monitor immune dysfunction in critically ill septic patients. Whole bloo...
ORGANISM(S): Homo sapiens 
2014-02-04 | E-GEOD-54514 | biostudies-arrayexpress
UnknownThe effects of quality improvement for depression in primary care at nine years: results from a randomized, controlled group-level trial.
Not available
S-EPMC2614007 | biostudies-literature
UnknownHigh BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CALGB) study.
Not available
S-EPMC2396728 | biostudies-literature
Transcriptomicsregulatory T cells in human pregnancy
Transplacental immune programming refers to the concept that during pregnancy, significant crosstalk occurs between the maternal and fetal immune system, with consequent long‐term effects especially for the offspring. In this study, we searched for evidence of transplacental programming in cellul...
ORGANISM(S): Homo sapiens 
2013-11-04 | E-GEOD-31976 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human peripheral blood mononuclear cells in sepsis
To identify signature genes that help distinguish (1) sepsis from non-infectious causes of systemic inflammatory response syndrome, (2) between Gram-positive and Gram-negative sepsis. Experiment Overall Design: A total of 70 critically ill patients (46 sepsis and 24 control) were enrolled in a singl...
ORGANISM(S): Homo sapiens 
2009-04-12 | E-GEOD-9960 | biostudies-arrayexpress
UnknownGut Microbiota-Generated Phenylacetylglutamine and Heart Failure.
Not available
S-EPMC9851997 | biostudies-literature
TranscriptomicsRadical prostatectomy specimens with and without TMPRSS2:ERG fusion from 139 patients with prostate in a Toronto cohort
Prostate tumors with the gene fusion TMPRSS2:ERG have been reported to have a significantly higher risk of recurrence compared with tumors lacking the fusion. Tumors from 139 patients who underwent radical prostatectomy were analyzed for the expression of 502 cancer-related genes to identify genes d...
ORGANISM(S): Homo sapiens 
2009-10-22 | E-GEOD-18655 | biostudies-arrayexpress
TranscriptomicsExpression profiling of critically ill influenza and bacterial pneumonia patients, also influenza vaccination recipients
Longitudinal Gene expression profiling of whole blood from critically ill influenza and bacterial pneumonia patients. In addition before vs 7 days post influenza vaccination volunteer samples are assayed. 3 groups of samples. First is bacterial pneumonia patients with 6 subjects sampled for up to ...
ORGANISM(S): Homo sapiens 
2011-06-30 | E-GEOD-20346 | biostudies-arrayexpress
TranscriptomicsBlood transcriptome of human bacterial and influenza A pneumonia
Introduction: Diagnosis of severe influenza pneumonia remains challenging because of the lack of correlation between presence of influenza virus and patient’s clinical status. We conducted gene expression profiling in the whole blood of critically ill patients to identify a gene signature that would...
ORGANISM(S): Homo sapiens 
2012-08-14 | E-GEOD-40012 | biostudies-arrayexpress
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