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ProteomicsGenotyping, generation and lysine 2-hydroxyisobutyrylation identification of the first human autosomal dominant osteopetrosis type II specific induced pluripotent stem cells
Background: Autosomal dominant osteopetrosis type II (ADO2) is a rare human genetic disease that has been broadly studied as an important osteopetrosis model; however, there are no disease-specific induced pluripotent stem cells (ADO2-iPSCs) that may be valuable for understanding the pathogenesis an...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD014227 | Pride
Osteopetrosis Whole exome sequencing Ipscs 2-hydroxyisobutyrylation Clcn7 
ProteomicsLiver proteomic reveals the key proteins involved in host immune response to sepsis
Sepsis is a serious infection-induced response in the host,which can lead to organ dysfunction. It is of great importance to unravel the relationship between sepsis and host immune response and its mechanisms of action. Liver is one of the most vulnerable organs in sepsis, however, the specific path...
ORGANISM(S): Rattus Norvegicus 
2022-11-15 | PXD037868 |
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