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MetabolomicsELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous disease with distinct molecular subtypes described as classical/progenitor and basal-like/squamous PDAC. We hypothesized that integrative transcriptome and metabolome approaches can identify candidate genes whose inactivation contributes to ...
2024-04-02 | MTBLS9418 | MetaboLights
UnknownA Transfer Hydrogenation Approach to Activity-Based Sensing of Formate in Living Cells.
Not available
S-EPMC11487638 | biostudies-literature
Unknown<i>In vivo</i> validation of the palmitoylation cycle as a therapeutic target in <i>NRAS</i>-mutant cancer.
Not available
S-EPMC11957127 | biostudies-literature
UnknownChanges in neurotensin signalling drive hedonic devaluation in obesity.
Not available
S-EPMC12119351 | biostudies-literature
UnknownPseudogene PTENP1 functions as a competing endogenous RNA to suppress clear-cell renal cell carcinoma progression.
Not available
S-EPMC4265235 | biostudies-literature
UnknownMolecular effects of indoor tanning.
Not available
S-EPMC11185634 | biostudies-literature
UnknownMolecular effects of indoor tanning.
Not available
S-EPMC12700204 | biostudies-literature
UnknownAmyloid negativity in patients with clinically diagnosed Alzheimer disease and MCI.
Not available
S-EPMC4831042 | biostudies-literature
MetabolomicsArginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
Defective arginine synthesis, due to the silencing of argininosuccinate synthase 1 (ASS1), is a common metabolic vulnerability in cancer, known as arginine auxotrophy. Understanding how arginine depletion kills arginine-auxotrophic cancer cells will facilitate the development of anti-cancer therapeu...
2019-11-07 | MTBLS745 | MetaboLights
UnknownA physical map for the Amborella trichopoda genome sheds light on the evolution of angiosperm genome structure.
Not available
S-EPMC3219971 | biostudies-literature
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