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TranscriptomicsThe Role of Interleukin-11 in the Development of the Autoimmune Response in Multiple Sclerosis
Our results introduce interleukin (IL)-11 as a new cytokine that may play a role in the development of the autoimmune response in patients with relapsing remitting multiple sclerosis (RR MS). IL-11 was found to be the highest up-regulated cytokine in the serum and cerebrospinal fluid (CSF) from pat...
ORGANISM(S): Homo sapiens 
2015-05-15 | E-GEOD-59085 | biostudies-arrayexpress
Proteomicsthe proteomics of IGFBP6 in endothelial cells (HUVECs)
To unravel the direct mechanism of the anti-inflammatory effects of IGFBP6 in ECs, we analysed HUVECs treated with either adenovirus-Flag-IGFBP6 (Ad-IGFBP6) or control adenovirus (Ad-NC). We precipitated IGFBP6 from overexpressed ECs followed by mass spectrometry.
ORGANISM(S): Homo Sapiens 
2024-05-13 | PXD052204 |
ProteomicsTandem mass tag-based quantitative proteomic analysis reveals proteins involved in hemolytic hyperbilirubinemia-induced brain injury in rats
Hemolytic hyperbilirubinemia-induced brain injury (HHIBI) can cause neonatal death, and survivors often have neurological sequelae, including irreversible motor sensitive and cognitive abnormalities. However, the underlying mechanisms remain elusive. By identifying differentially abundant proteins (...
ORGANISM(S): Rattus Rattus 
2023-04-18 | PXD041604 |
ProteomicsTemporal proteomics characterization of COVID-19 patient sera
We enrolled 37 SARS-CoV-2 positive patients including 17 short course (SC) COVID-19 patients (twice viral RNA detection negative over 24 hrs) and 20 COVID-19 long course (LC) COVID-19 patients. We also included 35 SARS-CoV-2 negative patients as control group. We collected 224 inactive serum samples...
ORGANISM(S): Homo Sapiens 
2022-07-26 | PXD035471 |
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