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TranscriptomicsDeep Sequence Analysis of non-small cell lung cancer: Integrated analysis of gene expression, alternative splicing, and single nucleotide variations in lung adenocarcinomas with and without oncogenic KRAS mutations
In this manuscript, we have used RNA-Sequencing experiment to obtain and integrate a variety of genomic features in order to identify signaling pathways that are associated to mutant KRAS lung tumors. 8 lung adenocarcinomas with mutant KRAS in lung tumors and 8 lung adenocarcarcinomas without KRAS m...
ORGANISM(S): Homo sapiens 
2012-06-07 | E-GEOD-34914 | biostudies-arrayexpress
TranscriptomicsAn Integrated Model of the Transcriptome Landscape of HER2-Positive Breast Cancer
The goal of our study is to build an integrated transcriptome landscape model for HER2 positive breast tumors and identify the crucial signaling pathways associated with HER2 tumors. Genomic features include, 685 genes that were differentially expressed only in HER2-positive tumors, 102 genes that w...
ORGANISM(S): Homo sapiens 
2013-12-06 | E-GEOD-45419 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of garlic induced hepatoprotection against alcoholic fatty liver
Alcohol induced fatty liver cause a dangerous health problem and is the major cause of morbidity and mortality worldwide. Garlic (Allium sativum) is documented to possess anti-fatty liver properties. However the exact molecular mechanisms are unknown. The main aim of this experiment is to elucidate ...
ORGANISM(S): Mus musculus 
2012-10-01 | E-GEOD-40334 | biostudies-arrayexpress
MetabolomicsLongitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
ProteomicsProteomic analysis of UCHL1 conditional knockout mice
Proteomic analysis of osteoclast precursor cells of UCHL1 conditional knockout mice and wild-type mice was performed
ORGANISM(S): Mus Musculus 
2024-08-14 | PXD052578 |
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