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MetabolomicsHuman umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical studies to clinical settings has necessitated the exploration o...

2023-07-25 | MTBLS7759 | MetaboLights
UnknownShibi Tea (Adinandra nitida) and Camellianin A Alleviate CCl4-Induced Liver Injury in C57BL-6J Mice by Attenuation of Oxidative Stress, Inflammation, and Apoptosis.
Not available
S-EPMC9332116 | biostudies-literature
UnknownDevelopment of an indirect ELISA for Duck circovirus detection based on prokaryotically expressed antigen.
Not available
S-EPMC12502210 | biostudies-literature
UnknownHow Status Quo Bias Shapes Willingness, Uptake, and Adherence to PrEP Among Chinese MSM: A Behavioral Economics Perspective.
Not available
S-EPMC12924801 | biostudies-literature
ProteomicsUrinary proteome analysis of acute kidney injury in the post-cardiac surgery patients using high-resolution mass spectrometry
Acute kidney injury (AKI) associated with cardiac surgery may increase mortality and incidence rate of chronic kidney disease in critically ill patients. One purpose of this study was to investigate the possible correlations between urinary proteomic changes and cardiac surgery-related AKI.
ORGANISM(S): Homo Sapiens 
2022-03-16 | PXD032344 |
ProteomicsSelenium Supplementation Elevated SELENBP1 to Inhibit Fibroblast Activation in Pulmonary Arterial Hypertension
Prophylactic selenium supplementation could effectively improve hemodynamics and pulmonary vascular remodeling in monocrotaline-induced pulmonary hypertension rat models. We scanned the selenium-related proteins through proteomic profiles on pulmonary artery branches of monocrataline rats versus con...
ORGANISM(S): Rattus Norvegicus 
PXD056117 |
ProteomicsN-glycopeptide Signatures in Liver Diseases
(1) A N-glycopeptide method based on 18O/16O C-terminal labelling to obtain comparisons of serum from patients with HBV-related hepatocellular carcinoma (HCC-O18 labelling) and HBV-related liver cirrhosis (LC-O16 labelling) (2) MRM verification of N-glycopeptide alterations
ORGANISM(S): Homo Sapiens 
2019-09-10 | PXD013586 |
ProteomicsAntipsychotic cardiotoxicity and its mechanisms
Antipsychotic (AP) drugs are common agents for treating mental disorders such as schizophrenia, bipolar disorder, and major depressive disorder. Overall AP prescription increased 3.8-fold, while second-generation AP (SGA) prescriptions increased 18.1-fold during a 16-year follow-up. The increased us...
ORGANISM(S): Mus Musculus 
2021-12-22 | PXD030588 |
ProteomicsNuclear polysaccharides maintain H3K9me3-heterochromatin and genomic stability
Polysaccharides are traditionally confined to the cell surface and extracellular space, whereas their nuclear roles remain unclear. Here, we show that N-glycans are present in the nucleus and modify inner nuclear membrane (INM) proteins across multiple cell types. Disruption of INM protein N-glycosy...
ORGANISM(S): Mus Musculus 
2025-12-30 | PXD072505 |
UnknownNegative Pressure Dressings to Prevent Surgical Site Infection After Emergency Laparotomy: The SUNRRISE Randomized Clinical Trial.
Not available
S-EPMC11773404 | biostudies-literature
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