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TranscriptomicsOrientia tsutsugamushi, the agent of scrub typhus, induces an inflammatory program in human macrophages
Scrub typhus is a life-threatening disease caused by Orientia tsutsugamushi, a bacterium that mainly infects endothelial cells in vitro and in vivo. Evidence suggests that the interaction of O. tsutsugamushi with myeloid cells may play a pivotal role in O. tsutsugamushi infection. We showed here tha...
ORGANISM(S): Homo sapiens 
2013-01-29 | E-GEOD-38194 | biostudies-arrayexpress
TranscriptomicsOrientsia tsutsugamushi stimulates an original gene expression program in human monocytes: relationship with gene expression in patients with scrub typhus
Orientia tsutsugamushi, an obligate intracellular bacterium, is the causative agent of scrub typhus. As O. tsutsugamushi is detected in circulating monocytes during acute phase of scrub typhus, we wondered if this organism was able to infect monocytes. We showed here that O. tsutsugamushi replicated...
ORGANISM(S): Homo sapiens 
2010-09-21 | E-GEOD-24247 | biostudies-arrayexpress
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