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ProteomicsRats, Brain, LC-MSMS - iTRAQ-Based Proteomics Analysis Reveals the Effect of Rhubarb in Rats with Ischemic Stroke
In our study, we apply isobaric tag for relative and absolute quantitation (iTRAQ) followed by multidimensional liquid chromatography and tandem MS analysis(LC-MS-MS). The iTRAQ labeling were performed according to the manufacturer's protocol (Applied Biosystems).8 groups of samples were labeled and...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-24 | PXD006437 | Pride
Lc-msms Brain Rats 
UnknownSingle-cell RNA sequencing depicts the local cell landscape in thyroid-associated ophthalmopathy.
Not available
S-EPMC9418739 | biostudies-literature
ProteomicsTo identify the phenol soluble modulins whose production are primarily affected by SarZ in Staphylococcus epidermidis
Phenol-soluble modulins (PSMs) are a class of short, amphipathic, α-helical peptides, which have strong cytolytic effects toward leukocytes and erythrocytes in S. epidermidis. SarZ is a key transcriptional regulator required for the expression of virulence factors. To determine whether the productio...
ORGANISM(S): Staphylococcus epidermidis RP62A 
2024-12-05 | PXD057952 | Pride
Phenol soluble modulins Staphylococcus epidermidis Lc-ms/ms 
ProteomicsACL1-HD-Zip IV complex revealed common mechanism in rice response to brown planthopper and drought. Being a small peptide, ACL1 might function through forming complex with other proteins. So that we searched the possible interacting proteins of ACL1 using the TurboID system.
Brown planthopper (BPH) is the most notorious insect pest to rice. Drought is the most commonly occurring global adversity. BPH infestation caused adaxially-rolled leaves and shrunk bulliform cells similar to drought. The bulliform-cell characteristic gene, ACL1, negatively regulated BPH resistance ...
ORGANISM(S): Oryza sativa (Rice) 
2024-08-13 | PXD052228 | Pride
Acl1 Cuticular wax Roc Bph Drought tolerance 
UnknownDefinition of a novel vascular invasion-associated multi-gene signature for predicting survival in patients with hepatocellular carcinoma.
Not available
S-EPMC6923904 | biostudies-literature
ProteomicsSalivary Protein Biomarker Detection of Saliva Secretion Disorder in a Primary Sjögren Syndrome Murine Model
Decreased salivary flow is one of the most common symptoms in primary Sjögren syndrome (pSS). The present study was designed to identify a salivary protein biomarker related to saliva secretion disorder in NOD/ShiLtJ mice, a pSS primary murine model. The stimulated saliva was collected from NOD/ShiL...
ORGANISM(S): Mus musculus (Mouse) 
2018-03-21 | PXD008199 | Pride
Biomarker  saliva secretion disorder  sjögren syndrome  saliva  differential proteomic analysis 
UnknownInfluence of 4-week or 12-week glucocorticoid treatment on metabolic changes in patients with active moderate-to-severe thyroid-associated ophthalmopathy.
Not available
S-EPMC8504830 | biostudies-literature
ProteomicsIntegrative proteomic and phosphoproteomic analyses revealed the regulation mechanism of Clematis terniflora DC. response to UV-B stress
Clematis terniflora DC. is used as traditional herb medicine since ancient China. The active substances in C.terniflora have been confirmed to be effective in treating disease like prostatitis. The UV light radiation is a common environmental factor that damage the plants and has an influence on the...
ORGANISM(S): Clematis terniflora (Sweet autumn clematis) 
2023-03-11 | PXD038136 | Pride
Clematis terniflora dc.  ultraviolet b  proteomic  phosphoproteomic 
UnknownAlterations in Spontaneous Neuronal Activity and Microvascular Density of the Optic Nerve Head in Active Thyroid-Associated Ophthalmopathy.
Not available
S-EPMC9354054 | biostudies-literature
ProteomicsProfile the composition of reconstituted nuclear speckles
Nuclear extract from Hela Cells are incubated with recombinant SON IDR2 protein, resulting condensates are spun down and the compostion profiled by mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2024-11-25 | PXD050371 | Pride
Nuclear speckles 
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