Sort   by:  
 Page size 
ProteomicsRadiation response in human cardiac endothelial cells investigated by DIA-MS
The endothelium is the barrier separating blood and tissue. Radiation-induced enhanced inflammation leading to permeability of this barrier may increase the risk of cardiovascular disease. The aim of this study was to investigate the onset of endothelial inflammatory pathways after radiation exposur...
ORGANISM(S): Homo sapiens (Human) 
2020-11-02 | PXD020735 | Pride
Ionizing radiation Proteomics Ddb2 Inflammation Endothelial cells Cgas-sting-pathway Data-independent acquisition Stat1 
ProteomicsProteomics on sera of mice following local high-dose heart irradiation
Background and Purpose: Cardiotoxicity is a well-known adverse effect of radiation therapy. Measurable abnormalities in the heart function indicate advanced and often irreversible heart damage. Therefore, early detection of cardiac toxicity is necessary to delay and alleviate the development of the ...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD024446 | Pride
Heart Proteomics Radiation therapy Inflammation Cytokines Data-independent acquisition Ionizing radiation Biomarker 
ProteomicsMurine hippocampus after radiation LC-MSMS
The impact of low-dose ionizing radiation (IR) on human brain has recently attracted attention due to increased use of IR for diagnostic purposes. The aim of this study was to investigate low-dose radiation response in hippocampus. Female C57Bl/6 mice were irradiated with 0 (control), 0.063, 0.125 o...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-06 | PXD015729 | Pride
Ionizing radiation Hippocampus Brain Label-free proteomics Creb signaling Accelerated aging 
TranscriptomicsFe ions and X-ray radiation exposure of Est2-immortalised human coronary artery endothelial cells - 1 day and 7 days post-irradiation
In recent years there is a growing epidemiological indication of excess risk of cardiovascular disease at low doses of ionizing radiation without a clear-cut threshold. It is proposed that damage to the vascular endothelium is critical in radiation-related cardiovascular diseases. In order to identi...
ORGANISM(S): Homo sapiens 
2017-10-02 | E-MTAB-5754 | biostudies-arrayexpress
Genomicse19c38e5-647a-4bfa-87f1-fec5646bcb9b - samples
The appearance of type 1 diabetes (T1D)-associated autoantibodies is the first and only measurable parameter to predict progression toward T1D in genetically susceptible individuals. However, autoantibodies indicate an active autoimmune reaction, wherein the immune tolerance is already broken. There...
EGAD00001005767 | EGA
GenomicsRNA-seq study of longitudinal blood cell samples from children at risk of type 1 diabetes
The appearance of type 1 diabetes (T1D)-associated autoantibodies is the first and only measurable parameter to predict progression toward T1D in genetically susceptible individuals. However, autoantibodies indicate an active autoimmune reaction, wherein the immune tolerance is already broken. There...
EGAS00001004071 | EGA
GenomicsDIABIMMUNE Transcriptomics DAC
Data Access Committee EGAC00001001443
EGAC00001001443 | EGA
TranscriptomicsAn integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiation
The aim of this dataset was to study in detail the transcription kinetics initiated by cytokines IL-12 and IL-4 in early differentiation of Th1 and Th2 cells, respectively. Total RNA obtained from activated and IL-12 or IL-4 & anti-IL-12 treated cord blood CD4+ T cells, 12, 24, 48, and 72 hours afte...
ORGANISM(S): Homo sapiens 
2012-11-09 | E-GEOD-32959 | biostudies-arrayexpress
Sort   by:  
 Page size