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From an animal production and health perspective, our understanding of the metabolites in ruminant biofluids, particularly rumen fluid across different host species is poorly understood. Metabolomics is a powerful and sensitive approach for investigating low molecular weight metabolite profiles p...

2021-08-23 | MTBLS1717 | MetaboLights
We report that acetylation of H4K16 is a new marker of active enhancers and that some enhancers are marked by H3K4me1, MOF and H4K16ac but not by acetylated H3K27 or p300, suggesting that they are novel p300-independent regulatory elements. ChIP-seq for H4K16 acetylation in undifferentiated ES cells...
ORGANISM(S): Mus musculus 
We report that acetylation of H4K16 is a new marker of active enhancers and that some enhancers are marked by H3K4me1, MOF and H4K16ac but not by acetylated H3K27 or p300, suggesting that they are novel p300-independent regulatory elements. Gene expression in undifferentiated 46c (sox1-gfp) ES cells...
ORGANISM(S): Mus musculus 
H4K16ac is gained on hox loci and lost on pluripotency genes upon differentiation ChIP on chip over hox loxi and pluripotency genes for H4K16ac in undifferentiated ES cells and after 3 days of retinoic acid treatment
ORGANISM(S): Mus musculus 
Level of H4K16ac on highest and lowest expressed genes in undifferentiated ES cells 3 biological replicates in undifferentiated ES cells
ORGANISM(S): Mus musculus 
Genome wide gain and loss of H4K16ac upon differentiation correlated with changes in expression. Gene expression in undifferentiated ES cells, and cells after 3 days of differentiation in retinoic acid. 3 biological replicates with two technical replicates were performed for each sample.
ORGANISM(S): Mus musculus 
Transcription profiling of highly purified blood cells from normal individuals
ORGANISM(S): Homo sapiens 
WTCCC1 project Autoimmune Thyroid Disease (ATD) samples
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