Tb drugs - OmicsDI

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UNIPROT ID/AC

14331_SOLTU (1)
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4113.PGSC0003DMT400001418 (1)
4113.PGSC0003DMT400003947 (1)
4113.PGSC0003DMT400005135 (1)
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4113.PGSC0003DMT400013958 (1)
4113.PGSC0003DMT400014381 (1)
4113.PGSC0003DMT400015957 (1)
4113.PGSC0003DMT400016201 (1)
4113.PGSC0003DMT400022438 (1)
4113.PGSC0003DMT400027147 (1)
4113.PGSC0003DMT400027379 (1)
4113.PGSC0003DMT400029003 (1)
4113.PGSC0003DMT400031900 (1)
4113.PGSC0003DMT400034164 (1)
4113.PGSC0003DMT400035006 (1)
4113.PGSC0003DMT400035007 (1)
4113.PGSC0003DMT400038109 (1)
4113.PGSC0003DMT400040121 (1)
4113.PGSC0003DMT400040182 (1)
4113.PGSC0003DMT400041662 (1)
4113.PGSC0003DMT400043254 (1)
4113.PGSC0003DMT400045338 (1)
4113.PGSC0003DMT400047686 (1)
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CHEBI ID

CHEBI:27570 (4)
CHEBI:16811 (4)
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Metabolite Name

Inosine (4)
5-Hydroxyindoleacetic acid (3)
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Hexadecanedioic acid mono-L-carnitine ester (2)
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Lab affiliation

1. Africa Health Research Institute, Durban, South Africa 2. 3Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA 3. Center for AIDS Research and Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, USA (1)
Aix-Marseille Univ, CNRS, LISM, IMM FR3479, 13009 Marseille, France (1)
Biology Departament. Federal University of Ceara. Brasil, Ceara. (1)
Centro de Pesquisas em Biologia Molecular e Funcional (CPBMF), Instituto Nacional de Ciência e Tecnologia em Tuberculose (INCT-TB), Programa de Pós-Graduação em Biologia Celular e Molecular - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil (1)
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (1)
Director, Research Integrity and Compliance Review Office Associate Professor, Mycobacteria Research Laboratories Dept of Microbiology, Immunology,& Pathology Colorado State University Ft. Collins, CO (1)
Division of Chemical and Systems Biology, Department of Integrative Biomedical Science, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Science, University of Cape Town, South Africa. (1)
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (1)

IsPrivate

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Submitter Keywords

Ersilia (2)
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Classification

bacteria (26)

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Transcription profiling by array (63)
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Gene expression in M. tuberculosis and M. africanum infected tuberculosis patients prior to and following treatment

Differential gene expression in M. tuberculosis and M. africanum patients under TB treatment Gene expression analysis of whole blood RNA from tuberculosis patients prior to and following treatment

ORGANISM(S): Homo sapiens

2015-06-05 | E-GEOD-62147 | biostudies-arrayexpress

Lung-resident myeloid-derived suppressor cells display dual functionality in experimental tuberculosis

Using cell-based approaches and experimental mouse models for pulmonary TB we unveiled MDSCs as new myeloid populations directly interacting with Mycobacterium tuberculosis (Mtb). MDSCs readily phagocytosed Mtb, released proinflammatory (IL-6, IL-1M-NM-1) and immunomodulatory (IL-10) cytokines while...

ORGANISM(S): Mus musculus

2014-12-21 | E-GEOD-57124 | biostudies-arrayexpress

Tuberculosis Patients Blood Gene Expression Through Treatment (cured and end-of-treatment patients)

Background Accurate assessment of treatment efficacy would facilitate clinical trials of new anti-tuberculosis drugs. TB patients exhibit altered peripheral immunity which reverts during successful treatment. We hypothesised that these changes could be observed in whole blood transcriptome profiles...

ORGANISM(S): Homo sapiens

2012-08-09 | E-GEOD-36238 | biostudies-arrayexpress

Tuberculosis patients blood gene expression through treatment

ORGANISM(S): Homo sapiens

2012-08-09 | E-GEOD-31348 | biostudies-arrayexpress

Pain-killer carprofen elicits pleiotropic modes of bactericidal action with potential to reverse antimicrobial resistance in tuberculosis.

The alarming rise of antimicrobial resistance in Mycobacterium tuberculosis coupled with the shortage of new antibiotics has made tuberculosis (TB) control a global health priority. Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the growth of multi-drug resistant isolates of M. tuberculosis....

ORGANISM(S): Mycobacterium tuberculosis H37Rv

2020-08-15 | E-MTAB-6191 | biostudies-arrayexpress

Analysis of Dynamic Efficacy Endpoints of the Nix-TB Trial.

Not available

S-EPMC10249992 | biostudies-literature

Resistance to fluoroquinolones and second-line injectable drugs: impact on multidrug-resistant TB outcomes.

Not available

S-EPMC4487776 | biostudies-literature

A novel home-based method for preparing suspensions of anti-TB drugs.

Not available

S-EPMC10599413 | biostudies-literature

EMI_TB_PROTEOMICS_CSIC

Three complete TMTs for saliva and three complete TMTs for sputum samples from active tuberculosis patients (TB) and their household infected (LTI) and uninfected (nonLTI) contacts. Parallel Reaction Monitoring (PRM) analysis in sputum samples of infected and uninfected contacts to measure levels of...

ORGANISM(S): Human

2017-10-02 | MSV000081574 | MassIVE

Beste2007 - Genome-scale metabolic network of Mycobacterium tuberculosis (GSMN_TB)

Beste2007 - Genome-scale metabolic network of Mycobacterium tuberculosis (GSMN_TB) This model is described in the article: GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism. Beste DJ, Hooper T, Stewart G, Bonde B, Avignone-Rossa C, Bush...

2015-07-30 | MODEL1507180021 | BioModels

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