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ProteomicsTBC1D22B Regulates ER-to-Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast Cancer
The anterograde secretory pathway shapes the extracellular environment and the ability of cells to communicate, through the release of cytokines, growth factors, enzymes and extracellular matrix components, and through the regulation of the composition of the plasma membrane (PM). The underlying mol...
ORGANISM(S): Homo sapiens (Human) 
2025-08-21 | PXD060457 | Pride
Tbc1d22b Rab1b Apex 
UnknownTBC1D22B Regulates ER-to-Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast Cancer.
Not available
S-EPMC12631847 | biostudies-literature
UnknownAssociation of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer.
Not available
S-EPMC7170497 | biostudies-literature
UnknownTBC1 domain-containing proteins are frequently involved in triple-negative breast cancers in connection with the induction of a glycolytic phenotype.
Not available
S-EPMC11375060 | biostudies-literature
TranscriptomicsTBC1 domain-containing proteins are frequently involved in triple-negative breast cancers in connection with the induction of a glycolytic phenotype
Metabolic plasticity is a hallmark of cancer, and metabolic alterations represent a promising therapeutic target. Since cellular metabolism is controlled by membrane traffic at multiple levels, we investigated the involvement of TBC1 domain-containing proteins (TBC1Ds) in the regulation of cancer me...
ORGANISM(S): Homo sapiens 
2024-07-30 | GSE273321 | GEO
GenomicsTBC1 domain-containing proteins are frequently involved in triple-negative breast cancers in connection with the induction of a glycolytic phenotype
TBC1 domain-containing proteins are frequently involved in triple-negative breast cancers in connection with the induction of a glycolytic phenotype
PRJNA1141419 | ENA
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