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ProteomicsThe non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins
Mitochondrial protein import is essential for all eukaryotes. Here we show that the early diverging eukaryote Trypanosoma brucei has a non-canonical inner membrane (IM) protein translocation machinery. Besides TbTim17, the single member of the Tim17/22/23 family in trypanosomes, the presequence tran...
ORGANISM(S): Trypanosoma brucei 
2016-12-20 | PXD005484 | Pride
Trypanosoma brucei Rhomboid-like proteins Proteomics Silac Mitochondrial protein import Tbtim17 Rnai-mediated protein knockdown 
UnknownDivergent Small Tim Homologues Are Associated with TbTim17 and Critical for the Biogenesis of TbTim17 Protein Complexes in Trypanosoma brucei.
Not available
S-EPMC6010621 | biostudies-literature
UnknownA novel connection between Trypanosoma brucei mitochondrial proteins TbTim17 and TbTRAP1 is discovered using Biotinylation Identification (BioID).
Not available
S-EPMC9694106 | biostudies-literature
UnknownThe divergent N-terminal domain of Tim17 is critical for its assembly in the TIM complex in Trypanosoma brucei.
Not available
S-EPMC5926198 | biostudies-literature
UnknownProtein translocase of mitochondrial inner membrane in Trypanosoma brucei.
Not available
S-EPMC3340260 | biostudies-literature
UnknownNovel IM-associated protein Tim54 plays a role in the mitochondrial import of internal signal-containing proteins in Trypanosoma brucei.
Not available
S-EPMC8265390 | biostudies-literature
UnknownFunctional complementation analyses reveal that the single PRAT family protein of trypanosoma brucei is a divergent homolog of Tim17 in saccharomyces cerevisiae.
Not available
S-EPMC4346571 | biostudies-literature
UnknownCharacterization of the mitochondrial inner membrane protein translocator Tim17 from Trypanosoma brucei.
Not available
S-EPMC2954128 | biostudies-literature
UnknownDistinct structural motifs are necessary for targeting and import of Tim17 in Trypanosoma brucei mitochondrion.
Not available
S-EPMC10871166 | biostudies-literature
UnknownUnique Interactions of the Small Translocases of the Mitochondrial Inner Membrane (Tims) in Trypanosoma brucei.
Not available
S-EPMC10855554 | biostudies-literature
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