Sort   by:  
 Page size 
GenomicsGenome-wide maps of TCF7L1 binding during early adipogenesis
Here we show through genome-wide binding studies that transcription factor 7-like 1 (TCF7L1) represses structure-related genes during adipogenesis. Intriguingly, TCF7L1 is induced in a cell contact-dependent manner by confluency in preadipocytes and is required for adipocyte differentiation by repre...
ORGANISM(S): Mus musculus 
2011-09-02 | E-GEOD-31867 | biostudies-arrayexpress
ProteomicsChromatin immunoprecipitation of ectopic FLAG-tagged TCF7L1 followed by Mass Spectrome-try in H9-TCF7L1 Human Embryonic Stem Cells
TCF7L1 is a member of the T cell factor/Lymphoid enhancer factor (TCF/LEF) family of tran-scription factors that are part of the WNT/beta-CATENIN signaling pathway. TCF7L1 modulates transcription by interacting with other regulators on chromatin. TCF7L1 has been shown to be one of the key factors i...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD047582 | Pride
Mass spectrometry Human embryonic stem cells Immunoprecipitation Wnt/beta-catenin pathway Tcf7l1 
GenomicsTCF7L1 controls tuft cell differentiation
TCF7L1 controls tuft cell differentiation
PRJNA939140 | ENA
UnknownTcf7l1 directly regulates cardiomyocyte differentiation in embryonic stem cells.
Not available
S-EPMC6190650 | biostudies-literature
TranscriptomicsTCF7L1 knockdown in pancreatic cancer
RNAi mediated depletion of TCF7L1 increases activity of a Wnt-based reporter and imparts more aggressive tumor phenotypes in vitro in pancreatic cancer cell lines that express TCF7L1. We sought to determine what changes in transcription ocurred after RNAi mediated knockdown of TCF7L1 in these cells ...
ORGANISM(S): Homo sapiens 
2017-06-20 | GSE90926 | GEO
TranscriptomicsTCF7L1 controls tuft cell differentiation
To study the functions of Tcf7l1 during gut development, we have ablated Tcf7l1 specifically in the intestinal epithelium using Shh-Cre. To determine transcriptional changes upon loss of Tcf7l1, we have isolated EpCAM-positive epithelial cells from mouse embryos using fluorescence activated cell sor...
ORGANISM(S): Mus musculus 
2023-06-14 | GSE226187 | GEO
GenomicsTCF7L1 regulates colorectal cancer cell migration and invasion by repressing GAS1 expression (RNA-Seq)
TCF7L1 regulates colorectal cancer cell migration and invasion by repressing GAS1 expression (RNA-Seq)
PRJNA1006071 | ENA
GenomicsTCF7L1 regulates colorectal cancer cell migration and invasion by repressing GAS1 expression (ChIP-Seq)
TCF7L1 regulates colorectal cancer cell migration and invasion by repressing GAS1 expression (ChIP-Seq)
PRJNA1006070 | ENA
UnknownTCF7L1 regulates colorectal cancer cell migration by repressing GAS1 expression.
Not available
S-EPMC11139868 | biostudies-literature
UnknownTcf7l1 is required for spinal cord progenitor maintenance.
Not available
S-EPMC3177105 | biostudies-literature
Sort   by:  
 Page size