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TranscriptomicsTelomere length effect on genes near the telomere in myoblasts
We examined differential expression of genes within 10MBs of telomeres in myoblasts with long or short telomeres We offer telomere looping with telomere length as a partial mechanistic explanation for the changes gene expression that is observed. Compare expression of genes within 10MB of the telome...
ORGANISM(S): Homo sapiens 
2014-07-17 | E-GEOD-48973 | biostudies-arrayexpress
TranscriptomicsTelomere dysfunction and fusion during the progression of chronic lymphocytic leukaemia: evidence for a telomere crisis
We performed single-molecule telomere length and telomere fusion analysis in patients at different stages of chronic lymphocytic leukaemia (CLL). Our work identified the shortest telomeres ever recorded in primary human tissue reinforcing the concept that there is significant cell division in CLL. F...
ORGANISM(S): Homo sapiens 
2010-05-28 | E-GEOD-22016 | biostudies-arrayexpress
TranscriptomicsDistinctions between the stasis and telomere attrition senescence barriers in cultured human mammary epithelial cells
Molecular distinctions between the stasis and telomere attrition senescence barriers in cultured human mammary epithelial cells Normal human epithelial cells in culture have generally shown a limited proliferative potential of ~10-40 population doublings before encountering a stress-associated sene...
ORGANISM(S): Homo sapiens 
2010-05-28 | E-GEOD-16058 | biostudies-arrayexpress
UnknownTelomere Length Measurement by Molecular Combing.
Not available
S-EPMC7308456 | biostudies-literature
GenomicsSubtelomeric DNA methylation controls telomere length
DNAm control of telomere length
PRJEB110807 | ENA
ProteomicsDisruption of ZC3H15 Compromises Telomere Length Maintenance by Sequestering Telomerase within Cajal bodies
Telomere homeostasis, crucial for various biological processes, relies on telomerase activity. We identified ZC3H15 as a novel telomerase-interacting protein. Its deletion unexpectedly increased telomerase activity but led to shortened telomeres and cellular senescence. ZC3H15 interacts with telomer...
ORGANISM(S): Homo Sapiens 
2024-05-06 | PXD052036 |
GenomicsTelomere variant sequences encode a genetic blueprint for allele-specific telomere length (dataset 2)
Telomere variant sequences encode a genetic blueprint for allele-specific telomere length (dataset 2)
PRJNA1455523 | ENA
TranscriptomicsTelomere behavior in a hybrid yeast
Telomeres and the protein/RNA complexes involved in maintaining them are rapidly evolving systems across eukaryotes. Using two Saccharomyces species, S. cerevisiae and S. bayanus, we provide evidence that the telomere systems of these two closely related yeasts have evolved significantly apart and t...
ORGANISM(S): Saccharomyces bayanus 
2010-05-19 | E-GEOD-15877 | biostudies-arrayexpress
GenomicsTelomere variant sequences encode a heritable genetic blueprint for allele-specific telomere length (dataset 1)
Telomere variant sequences encode a heritable genetic blueprint for allele-specific telomere length (dataset 1)
PRJNA1371950 | ENA
ProteomicsDIA proteomic profiling of conditioned media from human umbilical cord mesenchymal stem cells with different telomere lengths
Human umbilical cord mesenchymal stem cells (hUMSCs) were isolated from the Wharton’s jelly of 50 neonatal umbilical cords. Telomere length was determined in passage 1 hUMSCs using terminal restriction fragment analysis (TRF). Five hUMSC samples with the shortest telomeres (bottom 10%) and five samp...
ORGANISM(S): Homo sapiens (Human) 
2026-10-07 | PXD082583 | Pride
Humscs Telomere length Conditioned medium Quantitative proteomics Human umbilical cord mesenchymal stem cells Secretome Dia proteomics 
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