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MetabolomicsTranscriptional Shift and Metabolic Adaptations during Leishmania Quiescence Using Stationary Phase and Drug Pressure as Models

Microorganisms can adopt a quiescent physiological condition which acts as a survival strategy under unfavourable conditions. Quiescent cells are characterized by slow or non-proliferation and deep down-regulation of processes related to biosynthesis. Although quiescence has been described mostly...

2022-02-23 | MTBLS4046 | MetaboLights
MetabolomicsIn plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids (Imaging MS assays)

Tapping into the metabolic cross-talk between a host and its virus can reveal unique strategies employed during infection. Viral infection is a dynamic process that generates an evolving metabolic landscape. Gaining a continuous view into the infection process is highly challenging and is limited...

2018-11-29 | MTBLS769 | MetaboLights
MetabolomicsIn plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids (GC- and LC-MS assays)

Tapping into the metabolic cross-talk between a host and its virus can reveal unique strategies employed during infection. Viral infection is a dynamic process that generates an evolving metabolic landscape. Gaining a continuous view into the infection process is highly challenging and is limited...

2018-11-29 | MTBLS767 | MetaboLights
MetabolomicsAntibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

Background

Antibiotic treatment has a well-established detrimental effect on the gut bacterial composition, but effects on the fungal community are less clear. Bacteria in the lumen of the gastrointestinal tract may limit fungal colonization and invasion. Antibiotic drugs t...

2020-09-28 | MTBLS1846 | MetaboLights
TranscriptomicsTime-course in rice leaves of the temperature shift experiment
Time-course transcriptional profiling of rice leaf of the temperature shift experiment in a growth chamber. This experiment was performed to validate the results of field transcriptomic modeling. Rice leaves (cv. Norin8) were collected at 2:00 and 14:00 on the day -1, 2, 4 and 6 from the temperature...
ORGANISM(S): Oryza sativa 
2012-12-07 | E-GEOD-36595 | biostudies-arrayexpress
MetabolomicsHuman milk as infantile Super Food - the effect of dietary choices and supplementation on the shift of lipidomic profile during different stages of lactation
The objective of this project was to establish an advanced analytical method leveraging high-resolution mass spectrometry LC-HRMS to comprehensively profile the human milk lipidome. Mass spectrometry resolves and quantifies compounds based on a fundamental physical metric: the mass-to-charge ratio. ...
2026-09-22 | MTBLS15678 | MetaboLights
GenomicsTemperature shift under anaerobic conditions
Temperature shift under anaerobic conditions
PRJNA507430 | ENA
ProteomicsProteomic profiling of CHO cell temperature shift
The reduction of cell culture temperature (i.e. temperature-shift) is a method used to extend the viability of some commercial cell culture processes and improve product quality. We utilised LC-MS/MS to profile the proteome in temperature shifted cells as well as those a normal physiological tempera...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2024-08-10 | PXD053492 | Pride
Temperature shift Recombinant therapeutic protein Biopharmaceutical manufacturing Chinese hamster ovary cells 
ProteomicsYeast proteomic analysis upon temperature shift
DIA/SWATH analysis of yeast upon temperature shift.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-06-28 | PXD016320 | Pride
Proteomics Dia S cerevisiae Swath Puf6 Yeast 
TranscriptomicsPrp4-1 temperature shift
Prp4-1 and wt strains were grown at 26°C to A600 of 1.0, then an equal volume of 48°C media was added to bring the temperature to 37°C. Both strains were allowed to grow at 37°C and samples were taken at 0 (before shift), 5, 15, 30, 60, and 120 mins after shift to restrictive temperature. Keywords =...
ORGANISM(S): Saccharomyces cerevisiae 
2002-04-16 | GSE34 | GEO
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