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In order to metastasize, few cells need to detach from the primary tumor, and transition through the circulation to distant sites to establish new solid tumor metastases. The gene expression changes occurring between these transitions are poorly understood, and controversial findings have been repor...
ORGANISM(S): Homo sapiens 
Gelsemium sempervirens L. (Gelsemium) is a traditional medicinal plant which at ultra-low doses is employed as anxiolytic and antidepressant, but consistent evidence is lacking and the possible mechanisms involved at the level of nervous system are largely unknown. In this study we have investigated...
ORGANISM(S): Homo sapiens 
Decreased oocyte developmental potential is an important factor affecting fertility and embryonic development. Increasingly evidence is suggested that the decline in oocyte quality caused by aging after in vitro ovulation is a limiting factor affecting the development of assisted reproductive techno...
ORGANISM(S): Mus Musculus 
2022-11-23 | PXD038293 |
Marek's disease virus (MDV) strain GX0101 was the first reported field strain of recombinant gallid herpesvirus type 2 (GaHV-2). However, the splenic proteomics study of MDV strain GX0101 infected chicken was still unclear. In this study, GX0101 was used to infect the chicken spleen in order to an...
ORGANISM(S): Gallus Gallus 
2023-04-06 | PXD041364 |
Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is a tumor suppressor that negatively regulates cell survival and proliferation by antagonizing phosphatidylinositol 3-kinase(PI3K)/protein kinase B(PKB/Akt) signaling. Loss of heterozygosity (LOH) of PTEN, reduced expression of PTEN a...
ORGANISM(S): Mus musculus 
The rates at which lesions are removed by DNA repair can vary widely throughout the genome with important implications for genomic stability. We measured the distribution of nucleotide excision repair (NER) rates for UV induced lesions throughout the yeast genome. By plotting these repair rates in r...
ORGANISM(S): Saccharomyces cerevisiae 
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