Sort   by:  
 Page size 
UnknownTENT5-mediated polyadenylation of mRNAs encoding secreted proteins is essential for gametogenesis in mice.
Not available
S-EPMC11193744 | biostudies-literature
UnknownInhibition of FAM46/TENT5 activity by BCCIPα adopting a unique fold.
Not available
S-EPMC10075960 | biostudies-literature
GenomicsThe C-terminal region of TENT5 Proteins Drives ER-associated mRNA Polyadenylation via FNDC3 interaction [RNA-seq]
The C-terminal region of TENT5 Proteins Drives ER-associated mRNA Polyadenylation via FNDC3 interaction [RNA-seq]
PRJNA1446833 | ENA
GenomicsThe C-terminal region of TENT5 Proteins Drives ER-associated mRNA Polyadenylation via FNDC3 interaction [TAIL-Seq]
The C-terminal region of TENT5 Proteins Drives ER-associated mRNA Polyadenylation via FNDC3 interaction [TAIL-Seq]
PRJNA1446862 | ENA
OtherThe C-terminal region of TENT5 Proteins Drives ER-associated mRNA Polyadenylation via FNDC3 interaction [TAIL-Seq]
Spatial regulation of mRNA polyadenylation is a key emerging mechanism shaping cellular function. The TENT5/FAM46 family comprises four non-canonical poly(A) polymerases that stabilize transcripts encoding ER-targeted proteins, with mutations linked to diseases of professional secretory cells. Using...
ORGANISM(S): Homo sapiens 
2026-05-14 | GSE326755 | GEO
TranscriptomicsThe C-terminal region of TENT5 Proteins Drives ER-associated mRNA Polyadenylation via FNDC3 interaction [RNA-seq]
Spatial regulation of mRNA polyadenylation is a key emerging mechanism shaping cellular function. The TENT5/FAM46 family comprises four non-canonical poly(A) polymerases that stabilize transcripts encoding ER-targeted proteins, with mutations linked to diseases of professional secretory cells. Using...
ORGANISM(S): Homo sapiens 
2026-05-14 | GSE326742 | GEO
TranscriptomicsPolyadenylation of mRNAs encoding secreted proteins by TENT5 family of enzymes is essential for gametogenesis in mice
Cytoplasmic polyadenylation plays a vital role in gametogenesis, however, the participating enzymes and substrates in mammals remain unclear. Using knockout and knock-in mouse models, we describe the essential role of 4 TENT5 poly(A) polymerases in mice fertility and gametogenesis. TENT5B and TENT5C...
ORGANISM(S): Mus musculus 
2024-05-16 | GSE239661 | GEO
GenomicsPolyadenylation of mRNAs encoding secreted proteins by TENT5 family of enzymes is essential for gametogenesis in mice
Polyadenylation of mRNAs encoding secreted proteins by TENT5 family of enzymes is essential for gametogenesis in mice
PRJNA1000501 | ENA
ProteomicsTENT5 cytoplasmic non-canonical poly(A) polymerases regulate the innate immune response in animals
Innate immunity, the first line of host defense against pathogens, is tightly regulated both transcriptionally and post-transcriptionally. Here, through global transcriptome and proteome analyses in Caenorhabditis elegans, we uncover a modulation of the expression of secreted innate immunity effecto...
ORGANISM(S): Caenorhabditis elegans 
2022-05-31 | PXD023238 | Pride
Innate immunity Cytoplasmic polyadenylation Non-canonical polyadenylation Tent5 Direct rna sequencing Terminal nucleotidyltransferase C. elegans innate immunity 
GenomicsTENT5 cytoplasmic non-canonical poly(A) polymerases regulate the innate immune response in animals
TENT5 cytoplasmic non-canonical poly(A) polymerases regulate the innate immune response in animals
PRJNA686670 | ENA
Sort   by:  
 Page size