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UnknownGenome-Wide CRISPR Screen Identifies KEAP1 Perturbation as a Vulnerability of ARID1A-Deficient Cells.
Not available
S-EPMC11394604 | biostudies-literature
TranscriptomicsscRNA-seq from Trex1 KO in tumor
Single-cell RNA-seq data for Trex1 WT and KO mice from the tumor. Used for manuscript in submission at Science Advances.
ORGANISM(S): Mus musculus 
2026-03-25 | E-MTAB-16526 | biostudies-arrayexpress
GenomicsOpen chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity [DNase_seq].
The human body contains thousands of unique cell types, each with specialized functions. Cell identity is governed in large part by gene transcription programs, which are determined by regulatory elements encoded in DNA. To identify regulatory elements active in seven cell lines representative of di...
ORGANISM(S): Homo sapiens 
2011-06-29 | E-GEOD-30224 | biostudies-arrayexpress
UnknownHuman de novo mutation rates from a four-generation pedigree reference.
Not available
S-EPMC12240836 | biostudies-literature
MetabolomicsHERPES SIMPLEX VIRUS TYPE 1 IMPAIRS DENDRITIC CELL FUNCTION BY REMODELLING NEUTRAL LIPID METABOLISM AND INDUCING LIPID DROPLET ACCUMULATION
Herpes simplex virus type 1 (HSV-1) infects dendritic cells (DCs), professional antigen-presenting cells that initiate and regulate host antiviral responses. HSV-1 infects DCs limiting their maturation, migration to draining lymph nodes and T cell activation capacity, ultimately promotes their apopt...
2025-04-03 | MTBLS5163 | MetaboLights
UnknownTargeting PPAR-gamma counteracts tumour adaptation to immune-checkpoint blockade in hepatocellular carcinoma.
Not available
S-EPMC10423534 | biostudies-literature
UnknownA familial, telomere-to-telomere reference for human de novo mutation and recombination from a four-generation pedigree.
Not available
S-EPMC11326147 | biostudies-literature
UnknownBiguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport.
Not available
S-EPMC5239486 | biostudies-literature
UnknownA systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE).
Not available
S-EPMC1950885 | biostudies-literature
GenomicsOpen chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity [FAIRE_seq]
The human body contains thousands of unique cell types, each with specialized functions. Cell identity is governed in large part by gene transcription programs, which are determined by regulatory elements encoded in DNA. To identify regulatory elements active in seven cell lines representative of di...
ORGANISM(S): Homo sapiens 
2011-06-29 | E-GEOD-30225 | biostudies-arrayexpress
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