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TranscriptomicsIsolation of epiblast stem cells from pre-implantation mouse embryos
Pluripotent stem cells provide a platform to interrogate control elements that function to generate all cell types of the body. Despite their utility for modeling development and disease, the relationship of mouse and human pluripotent stem cell states to one another remains largely undefined. We h...
ORGANISM(S): Mus musculus 
2011-01-25 | E-GEOD-26814 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse ES cells and EpiSCs
The application of human embryonic stem (ES) cells in medicine; and biology has an inherent reliance on understanding the starting; cell population. Human ES cells differ from mouse ES cells and the; specific embryonic origin of both cell types is unclear. Previous; work suggested that mouse ES cell...
ORGANISM(S): Mus musculus 
2008-06-19 | E-GEOD-7866 | biostudies-arrayexpress
TranscriptomicsRapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells
Stem cell biology has garnered much attention due to its potential to impact human health through disease modeling and cell replacement therapy. This is especially pertinent to myelin-related disorders such as multiple sclerosis and leukodystrophies where restoration of normal oligodendrocyte funct...
ORGANISM(S): Mus musculus 
2011-10-02 | E-GEOD-31562 | biostudies-arrayexpress
TranscriptomicsGene expression in undifferentiated human ES cells - Agilent
The application of human embryonic stem (ES) cells in medicine and biology has an inherent reliance on understanding the starting cell population. Human ES cells differ from mouse ES cells and the specific embryonic origin of both cell types is unclear. Previous work suggested that mouse ES cells co...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-7900 | biostudies-arrayexpress
TranscriptomicsThe NIH Human Pluripotent Stem Cell Database (Agilent, mRNA)
To better understand the extent to which induced pluripotent stem cells (iPSCs) faithfully recapitulate the characteristics of embryonic stem cells (ESCs) under (undiff)erentiated condition, KSR condition and FBS condition and how both compare to somatic tissues under these conditions, we employed w...
ORGANISM(S): Homo sapiens 
2012-10-31 | E-GEOD-32923 | biostudies-arrayexpress
TranscriptomicsThe NIH Human Pluripotent Stem Cell Database (Illumina, snp)
Genotyping was performed on DNA samples matched to the RNA samples included in the NIH Human Pluripotent Stem Cell Database (Series GSE32923). Seventeen undifferentiated human embryonic stem cell lines and 11 human induced pluripotent stem cells were analyzed. Expanded descriptions of methods used a...
ORGANISM(S): Homo sapiens 
2012-10-31 | E-GEOD-35157 | biostudies-arrayexpress
TranscriptomicsThe NIH Human Pluripotent Stem Cell Database (Affymetrix, mRNA)
To broaden the appeal of the NIH Stem Cell Database, we analyzed a subset of undifferentiated human embryonic stem cell lines (5 lines in duplicate) on the Affymetrix platform. One standard culture protocol was used in conjunction with rigorous quality control. Expanded description of methods used a...
ORGANISM(S): Homo sapiens 
2012-10-31 | E-GEOD-33789 | biostudies-arrayexpress
TranscriptomicsThe NIH Human Pluripotent Stem Cell Database (Illumina, methylation)
Methylation profiling was performed on DNA samples matched to the RNA samples included in the NIH Human Pluripotent Stem Cell Database (Series GSE32923). Nineteen undifferentiated human embryonic stem cell lines and 5 human induced pluripotent stem cells were analyzed. Expanded descriptions of metho...
ORGANISM(S): Homo sapiens 
2012-10-31 | E-GEOD-34869 | biostudies-arrayexpress
TranscriptomicsThe NIH Human Pluripotent Stem Cell Database (Agilent, cgh)
Array comparative genomic hybridization was performed on DNA samples matched to the RNA samples included in the NIH Human Pluripotent Stem Cell Database (Series GSE32923). Twenty two undifferentiated human embryonic stem cell lines were analyzed. Expanded descriptions of methods used are available a...
ORGANISM(S): Homo sapiens 
2012-10-31 | E-GEOD-35735 | biostudies-arrayexpress
TranscriptomicsThe NIH Human Pluripotent Stem Cell Database (Agilent, miRNA)
MicroRNA profiling was performed on RNA samples matched to those included in the NIH Human Pluripotent Stem Cell Database (Series GSE32923). Twenty undifferentiated human embryonic stem cell lines and 4 human tissues were analyzed. Expanded descriptions of methods used are available at: http://stemc...
ORGANISM(S): Homo sapiens 
2012-10-31 | E-GEOD-34199 | biostudies-arrayexpress
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